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TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Eyelid cells share signaling components but differ in pathway activity.

Mutant mice help researchers understand hair growth and related genetic factors.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

Hair growth and development are controlled by specific signaling pathways.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Growth factors are crucial for hair development and could help treat hair diseases.

Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.

The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.

Knocking out certain genes in mice helps understand skin and hair growth problems.

Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.

EGF controls hair growth by regulating hair follicles' growth phases.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.

Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.

Some hair loss disorders are caused by genetic mutations affecting hair growth.

EGFR is essential for normal hair development and follicle differentiation.

EGFR helps control how hair grows and forms without needing p53 protein.

AP-2α and AP-2β are crucial for healthy skin and hair.

The best animal model for studying male-pattern baldness is the stumptailed macaque, not rats or mice.