Hague: A New Mouse Hair Mutation With an Unstable Semidominant Allele

    October 2002 in “ Genetics ”
    Christophe Poirier, Atsushi Yoshiki, Kyoko Fujiwara … Moriaki Kusakabe
    Studysummary This study mapped a spontaneous mouse hair mutation, "hague," to keratin genes on chromosome 15 but found no gene mutations in hague mice.
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    Research cited in this study 10

    1. Delayed Wound Healing in Keratin 6a Knockout Mice Molecular and Cellular Biology · 2000
    2. Characterization of a 300 Kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain Journal of Investigative Dermatology · 2000
    3. Expression of MK6a Dominant-Negative and C-Terminal Mutant Transgenes in Mice Has Distinct Phenotypic Consequences in the Epidermis and Hair Follicle Differentiation · 1999
    4. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    5. Gene-Knockout Mice With Abnormal Epidermal and Hair Follicular Development Journal of dermatological science · 1998
    6. A New Mutation in the Type II Hair Cortex Keratin hHb1 Involved in the Inherited Hair Disorder Monilethrix Human Genetics · 1997
    7. Mutations in the Hair Cortex Keratin HHB6 Cause the Inherited Hair Disease Monilethrix Nature Genetics · 1997
    8. Mice With a Null Mutation of the TGFα Gene Have Abnormal Skin Architecture, Wavy Hair, and Curly Whiskers and Often Develop Corneal Inflammation Cell · 1993
    9. The Secret Life of the Hair Follicle Trends in genetics · 1992
    10. Cyclic Hair Loss and Regrowth in Transgenic Mice Overexpressing an Intermediate Filament Gene The EMBO Journal · 1990