Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)

    May 2020 in “ bioRxiv (Cold Spring Harbor Laboratory) ”
    Huiming Li, Baozhen Yang, Xiujuan Zhang … Jinping Chen

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study found that hair-type tissues in hedgehogs show higher enrichment of immune-related genes compared to spine-type tissues, suggesting that spines evolved to protect against injuries and infections.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 9

    1. The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target During Hair Follicle and Nail Differentiation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    2. Keratin Gene Mutations in Disorders of Human Skin and Its Appendages Archives of Biochemistry and Biophysics · 2010
    3. The Naked Truth: Sphynx and Devon Rex Cat Breed Mutations in KRT71 Mammalian genome · 2010
    4. Epidermal Patterning and Induction of Different Hair Types During Mouse Embryonic Development Birth defects research · 2009
    5. Smad4-Dependent Desmoglein-4 Expression Contributes to Hair Follicle Integrity Developmental Biology · 2008
    6. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    7. Defective Trophoblast Function in Mice With a Targeted Mutation of Ets2 Genes & Development · 1998
    8. Hoxc13 Mutant Mice Lack External Hair Genes & Development · 1998
    9. The Secret Life of the Hair Follicle Trends in genetics · 1992

    Related research 1

    1. Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris) Scientific reports · 2020