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GlossaryWnt10b

protein crucial for activating hair follicle stem cells

Wnt10b is a protein that plays a crucial role in the regulation of hair growth and development. It is part of the Wnt signaling pathway, which is essential for various cellular processes, including cell proliferation, differentiation, and migration. In the context of hair, Wnt10b helps to activate hair follicle stem cells, promoting the growth of new hair.

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WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes

research WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes

197 citations , June 2009 in “American journal of human genetics”

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

research WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation

96 citations , June 2017 in “Nature Communications”

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

research Adenovirus-Mediated Wnt10b Overexpression Induces Hair Follicle Regeneration

77 citations , July 2012 in “Journal of Investigative Dermatology”

Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.

research WNT10A Promotes an Invasive and Self-Renewing Phenotype in Esophageal Squamous Cell Carcinoma

55 citations , March 2015 in “Carcinogenesis”

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

research The Balance of BMP6 and WNT10B Regulates the Telogen-Anagen Transition of Hair Follicles

35 citations , February 2019 in “Cell Communication and Signaling”

BMP6 and Wnt10b control whether hair follicles are resting or growing.

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community Better Than Minoxidil? Topical Sodium Valproate

in Research/Science 50 upvotes 6 months ago

Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

community Natural Remedies: Polyphenols and Hair Loss

20 upvotes 6 years ago

Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

community Do you keep gains if you stop microneedling?

in Microneedling 15 upvotes 1 month ago

Stopping microneedling may result in losing hair gains, as it enhances the effectiveness of treatments like minoxidil. Combining microneedling with minoxidil and finasteride is more effective than using microneedling alone.