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SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Vervet monkeys show physical changes like hair loss and scrotal color changes due to stress or nutrition issues.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Certain drugs that block specific enzymes can help treat prostate diseases.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.

The Mason gastric bypass is a better surgery for weight loss with fewer complications compared to other methods.

Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.

Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.

Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.

A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.

Targeting the actin cytoskeleton could improve skin healing and reduce scarring.

Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.

DHT affects testicular development and regulates spermatogenesis in some fish.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Chilled ATPv-supplemented saline best preserves hair grafts' key genes.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.

TLR2 is important for hair growth and can be targeted to treat hair loss.