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This study found that heat-killed Enterococcus faecalis EF-2001 promoted hair regrowth in mice, likely by increasing the expression of growth factors and marker genes.

In this study, Gardenia florida fruit extract promoted hair growth in vitro and in vivo by enhancing hair growth-promoting gene expression and increasing hair follicle number, size, and depth in mice.

This study found that Ashwagandha-derived nanovesicles increased cell proliferation, angiogenesis, and growth factor expression in vitro, suggesting they may have potential as a plant-based alternative or complement to current therapies for hair and skin conditions.

This study found that red LED photobiomodulation significantly enhanced both the metabolic activity and proliferation of human placenta-derived pericytes, alongside increased expression of angiogenic markers, suggesting a potential non-invasive approach to aid tissue repair and vascular regeneration.

In this pilot study, minoxidil-treated scalp skin grafts from hair loss patients on mice showed increased expression of key anti-aging biomarkers and hair regrowth, suggesting minoxidil as a potential anti-aging agent by boosting VEGF-A production in hair follicles.

In this in vitro study, Yifa Compound Prescription was reported to enhance human hair follicle growth and increase VEGF mRNA expression compared to blank serum.

This study found that loliolide enhanced hair growth-related functions in 3D dermal papilla spheroids by activating AKT/β-catenin signaling pathways, with increased expression of related growth factors and genes.

This study reported that the use of composite RGDmix hydrogel improved the survival and proliferation of human amniotic mesenchymal stem cells and increased growth factor expression, enhancing wound healing through the RGDSP/integrin αv/PI3K/AKT signaling pathway.

In this study, Natural Plant Extracts (NPE) promoted hair growth in mice by stimulating anagen growth and upregulating relevant gene expression, compared to controls with saline.

This study found that de-saponinated Camellia seed cake extract promotes hair growth in vitro and in vivo by enhancing dermal papilla cell proliferation and modulating signaling pathways and growth factor expression.

This study found that recombinant human type XVII collagen (rhCOL17A1) promotes hair growth by activating the Wnt/β-catenin and SHH/GLI signaling pathways and increasing type XVII collagen expression, with significant effects observed in both cell and mouse models.

Ashwagandha nanoparticles help hair grow by increasing a growth factor.

In this study, researchers identified eight compounds in Suaeda glauca and reported that its extract may improve hair loss by affecting VEGF, IGF-1 expression, and Wnt/β-catenin signaling, especially compound 4, in human cell models.

This study found that transplanting hair follicle bulge-derived stem cells in rats enhanced skin regeneration during expansion by differentiating into several skin-related cells and increasing the expression of growth factors.

This study found that baicalin activates Wnt/ß-catenin signaling in human dermal papilla cells, increasing alkaline phosphatase expression, growth factor expression, and promoting hair growth in mice.

This study found that MBN, an herbal extract fermented by Lactobacillus plantarum, promoted hair growth and increased related gene expression in C57BL/6 mice.

This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.

In this study, fish-derived collagen hydrolysate from tilapia scales improved hair growth and skin health in both cellular and mouse models, reducing oxidative stress and inflammation while enhancing hair quality and promoting beneficial gene expression.

In this study, researchers observed that amla extract promoted hair growth by enhancing cell proliferation and reducing 5α-reductase expression in human dermal papilla cells, suggesting it may be effective in preventing hair loss.

This study found that Limosilactobacillus reuteri NCHBL-005, derived from honeybees, may promote hair growth via a novel non-androgenic mechanism involving the Wnt/β-catenin signaling pathway, as it increased hair follicle size and number in mice and influenced related gene expression in human follicle cells.

This study observed that topical application of maslinic acid stimulated hair growth in mice comparably to minoxidil, possibly through the Wnt/β-catenin pathway and involving ciliary gene activity, highlighting increased levels of trichogenic gene expression and protein levels.

In this experimental study, the researchers observed that Platycladus orientalis leaf extract promoted hair growth by enhancing dermal papilla cell proliferation and increasing growth factor expression, particularly through ACK1 activation and modulation of Wnt/β-catenin signaling pathways in cultured human cells and a 12-week topical application.

In this study, researchers developed WS Biotin, a new water-soluble form of biotin, and found that it significantly improves water solubility compared to free biotin and enhances hair-related keratin expression, gene activity for hair growth in vitro, while also reducing melanin content in skin cells.

This study found that Ganoderma Lucidum extract and its active component, Ganoderic acid A, improved hair cell proliferation and growth factor expression in lab and clinical settings, demonstrating significant hair loss inhibition effects when used in shampoo and tonic formulations over 24 weeks.

This study found that citron seed oil promotes hair regrowth in a C57BL/6 mouse model by enhancing the transition to the growth phase, increasing hair follicle features and skin thickness, and inducing specific protein expressions that support hair regeneration.

This study found that in laboratory settings, dermal papilla cells cultured as spheroids showed significantly higher hair inductive potential and angiogenic factor expression compared to monolayer cultures.

In this study, topical tofacitinib significantly increased hair regrowth in mice compared to minoxidil or vehicle, potentially due to elevated VEGF levels and reduced inflammation.

This study found that human outer root sheath cells express VEGF receptor-2, and exogenous VEGF165 significantly stimulates their proliferation through activation of the ERK signaling pathway.

This study generated a gene-edited cashmere goat with improved cashmere yield and fiber length by integrating VEGF at the FGF5 site, offering insights into hair growth mechanisms.

This study concluded that using human umbilical cord blood mononuclear cells transfected with VEGF and FGF2 genes enhances skin wound healing in rats, demonstrating greater wound revascularization compared to controls.