21 citations,
July 2014 in “Clinics in Dermatology” Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.
11 citations,
October 2007 in “Bioorganic & Medicinal Chemistry Letters” Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.
5 citations,
October 2020 in “Skin appendage disorders” Oral dutasteride works better for hair loss, but has more sexual side effects; intralesional dutasteride is a possible alternative.
103 citations,
June 2007 in “Endocrinology and Metabolism Clinics of North America” Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
The new treatment regimen was effective in promoting significant hair growth in all 15 male patients with androgenic alopecia.
82 citations,
January 2000 in “Hormone Research in Paediatrics” DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
November 2023 in “Frontiers in cell and developmental biology” Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.
96 citations,
September 2008 in “Seminars in Cutaneous Medicine and Surgery” Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.
62 citations,
June 2013 in “JAMA Dermatology” Finasteride reduces Hidradenitis Suppurativa flare-ups in children and teens, but long-term safety is unknown.
55 citations,
July 2016 in “Dermatologic Therapy” Multiple treatments work best for hair loss.
47 citations,
August 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.
30 citations,
February 2003 in “Annals of Neurology” Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
8 citations,
February 2003 in “Annals of Neurology” Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.
4 citations,
April 2018 in “Journal of labelled compounds & radiopharmaceuticals” A new compound was effective for imaging prostate cancer in rats.
2 citations,
February 2003 in “Annals of Neurology” Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.
March 2006 in “Journal of The American Academy of Dermatology” Most patients with anal Pemphigus Vulgaris had repeated episodes but fully recovered with treatment, without long-term problems.
March 2006 in “Journal of The American Academy of Dermatology” Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.
17 citations,
December 2015 in “BMC Complementary and Alternative Medicine” A new plant extract from Avicennia marina could potentially be used to treat common hair loss.
17 citations,
November 1997 in “Andrology” Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.
59 citations,
April 2019 in “Psychoneuroendocrinology” Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
42 citations,
May 2010 in “Endocrinology” Mice with human gene experienced hair loss when treated with DHT.
70 citations,
May 2014 in “Annales d'endocrinologie” New genes and pathways are important for testosterone production and male sexual development.
19 citations,
January 2018 in “European Journal of Pharmaceutics and Biopharmaceutics” The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.
1 citations,
March 2015 in “Hair therapy & transplantation” New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
18 citations,
April 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
32 citations,
November 2017 in “Journal of Pharmaceutical Sciences” Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.
3 citations,
April 2021 in “Journal of Medicinal Chemistry” Finasteride may affect PNMT, causing side effects.
3 citations,
October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
17 citations,
August 2012 in “European journal of medicinal chemistry” New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.