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Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Dutasteride may help treat prostate cancer by causing cancer cells to shrink and die.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

The study suggests that analyzing DNA can help treat hair loss, but more research is needed.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

The supplement with Serenoa repens and Pygeum africanum significantly increased active hair growth and decreased rest phase hair in post-menopausal women with hair loss, with only mild digestive side effects.

Finasteride improves hair growth in men with androgenetic alopecia.

Male androgenetic alopecia (MAA) is a common, hereditary hair loss condition in men, linked to heart disease, and can be treated with minoxidil, finasteride, or hair transplantation.

Finasteride doesn't affect ovulation in normal women.

Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Plant-based treatments can effectively and safely treat hair loss.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Glioblastoma cells can make androgens, which might help the tumor grow.

Certain medications, especially 5-α reductase inhibitors and neuropsychiatric drugs, are often linked to erectile dysfunction.