A Comprehensive Review on Phytochemistry and Pharmacological Effects of Stinging Nettle (Urtica dioica)

May 2017 in “ Current traditional medicine ”

Mona Semalty, Lokesh Adhikari, Divya Semwal, Anurag Chauhan, Akash Mishra, Rupali Kotiyal, Ajay Semalty

Urtica dioica stinging nettle sterols fatty acids lectins terpenes phenylpropanes lignans coumarins aromatase inhibition 5 α-reductase inhibition

TLDR Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.

The review discussed the phytochemistry and pharmacological effects of Urtica dioica (stinging nettle), highlighting its traditional use for joint pain, arthritis, and prostate issues. The plant's roots and leaves contain bioactive compounds such as sterols, fatty acids, lectins, terpenes, phenylpropanes, lignans, and coumarins. These compounds contribute to various biological activities, including hypoglycemic, anti-inflammatory, antiproliferative, antioxidant, hypolipemic, antirheumatic, anticarcinogenic, and antiviral effects. The mechanisms of action include inhibition of aromatase, 5 α-reductase, cell proliferation, and Na+, K+-ATPase. The review provided a comprehensive overview of the plant's phytochemistry and pharmacology.

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