1 citations,
February 2022 in “Online journal of biological sciences” The document does not determine if adults with aphallia are fertile.
November 2020 in “Elsevier eBooks” Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
July 2019 in “Dermatología Cosmética, Médica y Quirúrgica” Small injections of dutasteride improved hair thickness in men with hair loss without major side effects.
13 citations,
December 2017 in “BMC Complementary and Alternative Medicine” The Asian herbal mix with Houttuynia cordata, Perilla frutescens, and green tea helped grow hair in mice.
3 citations,
May 2014 in “InTech eBooks” Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.
1 citations,
June 2017 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride use may cause sexual dysfunction; more research needed.
90 citations,
January 2021 in “Clinical Endocrinology” Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.
53 citations,
May 2010 in “PubMed” Spironolactone helps regrow hair in women with hair loss.
43 citations,
April 2017 in “Experimental Dermatology” Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.
32 citations,
February 2019 in “Journal of neurochemistry” Sex hormones affect brain injury differently in males and females.
26 citations,
December 2015 in “Journal of The European Academy of Dermatology and Venereology” New method measures female hair loss: Female Pattern Hair Loss Severity Index (FPHL-SI).
21 citations,
May 2017 in “International Journal of Dermatology” Overweight smokers have worse hair loss.
12 citations,
October 2013 in “The Prostate” Dutasteride and finasteride affect different cell types differently.
10 citations,
January 2010 in “PubMed” Adjuvants, diet changes, and laser therapy may improve male pattern hair loss.
7 citations,
August 2006 in “Experimental Neurology” Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
2 citations,
January 2008 in “Journal of Pakistan Association of Dermatology” Finasteride 1mg daily effectively increases hair growth and slows hair loss in men with male pattern baldness over two years.
April 2008 in “Blackwell Publishing Ltd eBooks” AGA causes permanent hair loss; minoxidil helps men, finasteride helps men, minoxidil somewhat helps women, estrogens/antiandrogens lack evidence for women.
74 citations,
January 2013 in “Expert Opinion on Biological Therapy” The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.
60 citations,
April 2010 in “General and Comparative Endocrinology” Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
55 citations,
March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
51 citations,
October 2012 in “International Journal of Immunopathology and Pharmacology” Finasteride works better than Serenoa repens for male hair loss.
32 citations,
December 2017 in “Journal of Drug Delivery Science and Technology” Minoxidil and caffeine in transfersomes improve hair growth treatment.
29 citations,
January 2009 in “International Journal of Trichology” Finasteride for hair loss may cause gynecomastia; doctors should inform patients.
17 citations,
September 2020 in “Journal of Endocrinological Investigation” Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.
5 citations,
May 2020 in “Pharmaceutical Research” Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
3 citations,
September 2019 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil effectively treats mild-moderate male hair loss, alone or combined with other therapies.
3 citations,
January 2010 in “Expert Opinion on Pharmacotherapy” No treatment fully stops excessive hair growth in women, but various methods can help manage it effectively.
2 citations,
January 2015 in “Journal of cosmetology & trichology” Need better hair loss treatments beyond minoxidil, finasteride, and transplants.
2 citations,
December 2013 in “Xenobiotica” Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
1 citations,
January 2015 in “Journal of Aesthetic & Reconstructive Surgery” Hair transplantation is the best treatment for hair loss, with new technologies improving results, and stem cell and gene therapies may treat severe baldness in the future.