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New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

Four-amino acid part makes enzyme sensitive to finasteride.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

Sebocytes play a key role in controlling androgen levels in human skin.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Orthosiphon stamineus leaf extract reduces oily skin and improves complexion better than zinc gluconate.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.