Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that in rodent models, the ability of D1 dopamine receptor activation to impair sensory gating is facilitated by 5α-reductase type 1, which produces allopregnanolone.

This study suggests that finasteride treatment may improve pulmonary immune response in mice following trauma and sepsis, indicating potential as a therapeutic option after major trauma.

This study suggests that the patchy thickening and reddish discoloration in rabbit skin during the hair cycle may be due to large anagen-phase hair follicles compressing the dermis and increased blood vessels causing redness.

In this study, a specific SNP in the A2M gene of Murrah buffaloes was significantly associated with increased fat production and higher fat and protein percentages in milk.

This study found that Ficus carica extract enhanced fertility markers, including hormone levels and reproductive organ activity, in rats of both sexes, suggesting potential benefits for managing fertility issues.

This study investigated the anti-inflammatory effects of a 940nm diode laser in Wistar rats with carrageenan-induced arthritis and found that a 74J/cm² energy density significantly reduced edema and restored function, whereas 171J/cm² neared thermal exposure limits for the skin.

This study found that women with polycystic ovary syndrome have higher insulin resistance and lower serum high-molecular weight adiponectin, which may play a role in the condition's pathogenesis.

This study evaluated androgen-induced hair loss and anagen induction mouse models, finding that Minoxidil and Pyrilutamide significantly promoted hair growth by decreasing androgen receptor protein levels and enhancing the Wnt/β-Catenin signaling pathway, supporting their use in studying novel treatments for androgenetic alopecia.

In this study, tempeh oil rich in PUFAs, particularly from black soybean, significantly down-regulated MMP-9 gene expression in UVB-irradiated mice skin, indicating potential for use in preventing skin photoaging.

This study found that ethanol extract and n-hexane fraction of rampai leaves may stimulate hair growth in rabbits, showing potential as an anti-alopecia treatment.

Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.

The study developed herbal shampoo formulations using isolated phytoconstituents, such as eugenol, rutin, menthol, and camphor, which demonstrated similar antifungal efficacy to ketoconazole but with improved safety and detergency, offering a promising alternative for managing seborrheic dermatitis.

In this study, transplantation of hair follicle stem cells and nerve growth factor-modified stem cells significantly reduced amyloid deposition and tau hyperphosphorylation in an Alzheimer's disease rat model, suggesting potential as a treatment option.

In this study, the application of human umbilical cord mesenchymal stem cell secretome significantly increased hair follicle count in fluconazole-induced alopecia in rats, although changes in epidermal thickness were not significant, suggesting a novel approach for hair restoration.

This study found that treating male rats with human hair follicle stem cells improved memory function impaired by streptozotocin and increased both neurotrophic and inflammatory markers, suggesting potential neuroprotective effects in this model.

This study examined the cytotoxic effects of arumanis mango rind extract and its fractions on T47D breast cancer cells, with results showing that ethanol extract and ethyl acetate fraction exhibited significant potential in reducing cell viability, similar to the effects of doxorubicin.

In this study, researchers developed a novel dry shampoo powder using traditional Indian botanicals and found that it demonstrated effective cleansing properties, favorable physicochemical characteristics, and no adverse effects in animal safety evaluations, offering an eco-friendly alternative to synthetic shampoos.

This study found that undiluted mint leaf extract effectively inhibited multidrug-resistant Staphylococcus aureus and killed Culex pipiens larvae, suggesting its potential as a biocontrol strategy around hospitals.

Dietary choices, especially fat type, can influence health.

This research found that liquid-state liposomes and niosomes may enhance finasteride delivery to pilosebaceous units in hamsters more effectively than gel-state vesicles or hydroalcoholic solution.

This study found that polyamines enhance genome integrity by facilitating homologous recombination-mediated DNA repair, suggesting a novel role for polyamines beyond promoting cell growth and proliferation.

This study demonstrated effective delivery of CRISPR/Cas9 components to dermal papilla cells in androgenic alopecia animals using ultrasound-activated nanoparticles, resulting in specific gene editing and hair growth recovery.

This study found that finasteride at 1 mg/day was the most effective dose for treating male pattern hair loss, with similar efficacy to 5 mg/day and better results than lower doses.

This study found that Transcutol P significantly enhanced the skin penetration of Finasteride in vitro, while cationic and anionic surfactants did not show such effects.

This study found that millimolar concentrations of minoxidil in the skin induced VEGF production through HIF-1 stabilization by inhibiting PHD-2, implying a molecular mechanism for hair growth promotion.

In this study, researchers demonstrated that in a mouse model, the stimulation of mammary tumor growth due to progesterone is primarily caused by its metabolite, 5αP, not progesterone itself.

This study found that both allogeneic and xenogeneic small extracellular vesicles from adipose tissue similarly enhanced soft tissue regeneration and wound healing in rat models, implying similar therapeutic effects across species.

This study found that pregnane derivatives with higher lipophilicity, like compound 9d, had stronger androgen receptor binding and greater antiandrogenic effects in rats, correlating relative binding affinity with log P values.

This study observed that glycine inhibited root growth and stimulated root hair development in habanero pepper seedlings, with ethylene signaling suggested to mediate these effects.

In this animal study, researchers found that finasteride reduced bacterial infection and inflammation in chronic bacterial prostatitis, with the greatest effect when combined with ciprofloxacin.