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    Neuroprotective and Immunomodulatory Effects of Human Hair Follicle Stem Cells on Streptozotocin-Induced Memory Impairment in Rats: Insights into Inflammation and Neurotrophic Mechanisms

    May 2025
    Etrat Hooshmandi, Elahe Rafiei, Maryam Owjfard … Mohammad Saied Salehi
    Studysummary This study found that treating male rats with human hair follicle stem cells improved memory function impaired by streptozotocin and increased both neurotrophic and inflammatory markers, suggesting potential neuroprotective effects in this model.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 4

    1. The Beneficial Effects of Chick Embryo Extract Preconditioning on Hair Follicle Stem Cells: A Promising Strategy to Generate Schwann Cells Cell proliferation · 2023
    2. Therapeutic Potential of Hair Follicle-Derived Stem Cell Intranasal Transplantation in a Rat Model of Ischemic Stroke BMC neuroscience · 2022
    3. Human Epidermal Neural Crest Stem Cells as Candidates for Cell-Based Therapies, Disease Modeling, and Drug Discovery Birth defects research · 2014
    4. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005