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This study found that keratinocyte stem/progenitor cell-conditioned medium significantly enhanced hair growth in mice and increased the proliferation of human hair follicle cells.

This study found that SA-MS hydrogel released Mo4+ ions which promoted healing of disease-impaired wounds by enhancing cell proliferation and angiogenesis, and through its photothermal effects addressed skin cancer-impaired wounds in mice.

This study examined variations in epidermal thickness and protein expression across different dog breeds, finding significant differences by anatomical site and breed, with associated mRNA and protein expression changes observed.

This study found that isolated red light may serve as an alternative for photo-immunotherapy without additional photosensitizers, as it did not reduce keratinocyte differentiation markers or increase photo-oxidative damage, unlike treatment with IL-4 or UVA1/blue light.

This study found that bulge-derived keratinocytes from human follicles were more resistant to differentiation compared to epidermal keratinocytes, possibly due to WIF-1 involvement.

This study suggests that porphyra-334 may have antiaging properties, promoting collagen synthesis, improving periorbital wrinkles, and supporting hair follicle growth through gene regulation.

In this study, researchers found that overweight and obese women with polycystic ovary syndrome showed adverse changes in glucose metabolism over time, highlighting the importance of early intervention to prevent cardiometabolic diseases.

This study found that 6-Gingerol significantly suppressed hair growth in mice by reducing hair follicle number and length, potentially through increased expression of MMP2 and MMP9.

This study demonstrated that genetic markers can predict human ear morphology with moderate to good accuracy, potentially aiding forensic identification in crime scene investigations where traditional DNA matches are unavailable.

This study found that the rs2228570 polymorphism of the VDR gene was associated with an increased risk of melanoma, while the rs731236 polymorphism was linked to a protective effect against the disease in Colombian patients.

In this study, extracts from three Polynesian plants—Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana—were found to increase dermal papilla cell proliferation and modulate hair growth-related gene expression, suggesting potential for stimulating hair growth.

This study reported that a newly developed UHPLC-MS/MS method detected illegal synthetic hair-growth compounds in 10% of 76 hair-growth products, highlighting the need for ongoing monitoring to protect public health.

This study found that stimulating toll-like receptor 5 via mucosal delivery of a flagellin-containing fusion protein effectively extended lifespan and enhanced healthspan in mice, including improved bone density and cognitive capacity.

This study found that the ethyl acetate extract of Fagraea berteroana fruits and its fraction FEAE-F0 promoted cell proliferation and modulated gene expression in hair follicle cells, suggesting potential for hair growth stimulation.

This study found that in mice, knockout of Rac1 and Rac3 in keratinocytes led to reduced white adipose tissue and revealed Rac-dependent paracrine pathways affecting pre-adipocyte differentiation.

In this study, researchers found that certain vitamin D receptor gene polymorphisms are significantly related to insulin concentration during a glucose tolerance test in young women with hyperandrogenism, but these polymorphisms did not affect bone metabolism or other biochemical parameters.

This study reports that despite rescuing neurulation and skin barrier defects, Grhl3 gene overexpression in mice leads to hearing impairment, hair loss, and other developmental abnormalities, highlighting low tolerance for Grhl3 dysregulation.

This study found that overexpression of β-catenin in bipotent Schwann-cell precursors promotes melanocyte development in limb areas by inducing MITF and repressing FoxD3, especially during a specific developmental timeframe.

This study found that topical application of Sinsun-yukza-hwan extract significantly increased hair density and thickness in a mouse alopecia model and enhanced expression of growth-related genes.

TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.

This study found that topical application of triiodothyronine (T3) can induce the transition of hair follicles from the telogen to the anagen phase in mice and stimulate hair shaft growth in vitro.

This study found that overexpression of the transcription factor Tcf3 accelerates keratinocyte migration and skin wound healing in mice, highlighting its potential as a therapeutic target for wound repair.

This study identified the Itpr3 gene as responsible for the tufted hair loss phenotype in the BTBR mouse strain.

This study suggests that topical T3 can induce hair follicles to enter the growth phase and may reverse graying in mice, with in vitro results supporting enhanced hair shaft growth.

This study found that applying supraphysiologic doses of topical T3 significantly accelerated wound healing in mice compared to a control vehicle, suggesting its potential as a cost-effective wound treatment.

This review discusses the role of TGM3 in skin and hair follicle biology, human tumor pathology, and genetic abnormalities, and reports no novel results; the authors highlight its potential as a cancer diagnostic biomarker.

In this study, physiological levels of free T3 significantly enhanced the survival of human hair follicles in vitro.

In this study, sequences upstream of the TGM3 gene were found to regulate epithelial-specific gene expression in keratinocytes, suggesting potential applications in gene therapy.

This study found that transgenic mice overexpressing human ATF3 showed hyperplastic and dysplastic changes in epithelial tissues, with a high incidence of oral cancer, suggesting potential oncogenic properties of ATF3.

This article is from the ASPS Education Network and does not report any new research findings.