4 citations,
September 2020 in “Annals of Translational Medicine” Concentrated nanofat helps mice grow hair by activating skin cells and may be used to treat hair loss.
3 citations,
February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
32 citations,
July 2012 in “Stem Cells Translational Medicine” Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.
66 citations,
March 2019 in “Cellular and Molecular Life Sciences” Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
1 citations,
February 2016 in “Cell Transplantation” Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
January 2019 in “Springer eBooks” Transplanting skin cells is a safe, effective, and affordable treatment for vitiligo.
306 citations,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
31 citations,
August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
8 citations,
January 2017 in “Methods in molecular biology” Stem cells rearrangement regenerates functional hair follicles, potentially treating hair loss.
5 citations,
April 2021 in “Biomedicines” The engineered skin substitute helped grow skin with hair on mice.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
610 citations,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
71 citations,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
61 citations,
October 1996 in “Development” Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.
17 citations,
December 2019 in “Stem Cells International” Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
15 citations,
July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.
9 citations,
March 2013 in “Expert opinion on biological therapy” Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
8 citations,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
3 citations,
May 2022 in “Oncogene” Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
1 citations,
January 2018 in “Stem cell biology and regenerative medicine” DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
1 citations,
November 2014 in “Elsevier eBooks” Future research should focus on making bioengineered skin that completely restores all skin functions.
February 2024 in “Frontiers in physiology” Lymphatic vessels are important for skin repair and could affect skin disease treatments.
68 citations,
June 2005 in “Expert Opinion on Therapeutic Targets” Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
20 citations,
November 2021 in “Frontiers in cell and developmental biology” Skin organoids from stem cells could better mimic real skin but face challenges.
5 citations,
October 2020 in “Frontiers in Cell and Developmental Biology” Reducing FOXA2 in skin cells lowers their ability to grow hair.
3 citations,
April 2022 in “International Journal of Molecular Sciences” Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
2 citations,
February 2023 in “International journal of molecular sciences” Tetrathiomolybdate reduces hair growth marker in skin cells by boosting harmful oxygen molecules, but effects can be reversed.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
January 2023 in “Theranostics” Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.
M-CSF-stimulated myeloid cells can turn into skin cells and help heal wounds and regrow hair.