Use of Induced Pluripotent Stem Cells in Dermatological Research

    July 2014 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    Jason Dinella, Maranke I. Koster, Peter J. Koch
    TLDR iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.
    The document discussed the potential of induced pluripotent stem cells (iPSCs) in dermatological research, particularly for treating conditions like hair loss and alopecia. iPSCs, derived from adult cells reprogrammed to an embryonic-like state, offered a promising avenue for generating hair follicles and other skin structures. They could differentiate into various cell types necessary for hair growth and model skin diseases for better understanding and treatment. However, challenges such as ensuring the safety and efficacy of iPSC-derived treatments, including the risk of teratoma formation and potential mutations during cell culture, needed to be addressed before clinical adoption. Despite these challenges, the potential for iPSC technology in developing novel therapies for genetic skin diseases was substantial.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 432 results

      community Please explain this Minoxidil phenomena

      in Minoxidil  56 upvotes 1 year ago
      The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  142 upvotes 10 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community 22 yr asian male 2 year fin results

      in Progress Pictures  135 upvotes 1 year ago
      The user "Top_Replacement_7777" shared their positive results with finasteride for hair loss. They asked about maintaining their hair with finasteride and the impact of vaping on hair growth. Another user reassured them that vaping wouldn't affect their progress.

    Similar Research

    6 / 1000+ results