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Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.

Phospholipase A2 enzymes play key roles in skin health and disease.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Editing the FGF5 gene in sheep increases fine wool growth.

Notch signalling helps skin cells differentiate and prevents tumors.

Vitamin D and its receptor may help prevent skin cancer.

THSG from a Chinese plant helps with aging and related diseases.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Different species use the same genes for tooth regeneration.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

Genes linked to wool fineness in sheep have been identified.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

The document concludes that significant investment in agricultural innovation is necessary to achieve global food security and nutrition.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

The tumor suppressor BRCA2 helps in cell division by bringing key proteins to the area where cells split.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.

CD61 is important for mouse tooth cell growth and works through Lgr5.

Pantethine may boost the immune system's ability to fight sarcoma.

Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.