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This study suggests that changes in expressed transcripts and splice isoforms may explain the transition from curly to straight fleece in Chinese Tan sheep as they age.

This study used Mendelian randomization to explore associations between 1400 blood metabolites and female-pattern hair loss, finding 23 metabolites and 4 metabolic ratios linked to the condition, while identifying fructose/mannose metabolism as a significant pathway.

This study identified specific genetic markers related to wool quality in Rambouillet sheep, which may aid breeders in making informed selection and breeding decisions for improved fine wool production.

This study examined how melatonin affects cashmere growth in goats, identifying potential molecular targets like ATP6V0A4, DLX3, and SMOC2 for enhancing cashmere yield and quality.

In this study of Zhexi Angora rabbits, researchers found that the fine-wool group exhibited lower fiber diameters and a higher hair follicle density than the coarse-wool group, and they identified key candidate genes potentially regulating wool quality through RNA-seq and genome resequencing techniques.

In this study, researchers developed a computational method called iEdgePathDDA that prioritizes anticancer drug candidates by analyzing changes in gene interactions, demonstrating superior performance compared to existing methods across colorectal, breast, and lung cancer datasets.

This study suggests a potential genetic component in CFA among Ridgeback dogs, but MLPH genotyping did not identify the MLPH gene as a contributing factor.

In this study, researchers found that while most genetic variants analyzed were not associated with PCOS in Polish women, the INSR rs1799817 polymorphism may be linked to acne, a symptom of the disorder.

This study found that both natural and environmental selection have significantly influenced the goat genome, revealing genetic loci tied to adaptation, fitness, and productive traits, more so than artificial selection, across various goat populations.

This study found that stage-specific epigenetic changes, particularly involving the gene PDGFC, may affect wool fiber development in Zhongwei goats, potentially serving as a biomarker for fur goat selection.

This study investigated the molecular mechanisms of hair follicle morphogenesis in Ordos fine-wool sheep, identifying differential genes related to primary and secondary hair follicles, and providing important insights for improving wool quality and breeding strategies.

This study found no significant difference in CUX1 core promoter methylation levels between different lambskin patterns in Hu sheep, suggesting other mechanisms influence CUX1 expression related to hair follicle development.

This study reported that alopecia in giant pandas may be linked to abnormal expression of several hair-related genes and pathways, providing insight for potential prevention and treatment strategies.

This study identifies key transcriptomic features and a necessary dermal niche for eccrine gland development, advancing potential regenerative approaches for these vital skin appendages.

This study revealed that BMP5 in onychofibroblasts may play a key role in the differentiation of nail matrix keratinocytes, highlighting transcriptional similarities between nail and hair structures.

This study identified genetic differences between Australian White Sheep and Hu Sheep that may explain their distinct pelage types, with a focus on subcutaneous adiposity and immunoregulation. The findings suggest potential targets for breeding climate-resilient sheep, enhancing our understanding of heat tolerance in these breeds.

In this single-cell transcriptomic study, researchers analyzed AA scalp samples and found distinct immune and nonimmune cell activation patterns, with elevated TH1/TH2 and JAK/STAT markers potentially contributing to hair follicle immune privilege disruption and disease severity.

This study found that overexpression of the FA2H gene in cashmere goats' hair follicle cells may enhance hair proliferation and regulate genes affecting cashmere fineness.

This study found that higher expression of the Hoxc13 gene in specific areas of hair follicles is associated with longer wool length in Gansu alpine fine-wool sheep.

In this study, ceruloplasmin and keratin 4 were identified as markers that differentiate between growing and resting phases in cashmere goat hair follicles, with keratin 4 being a potential marker for the onset of a new hair cycle.

This study found that Tibetan cashmere goats have genetic adaptations that contribute to their finer cashmere, possibly enhancing their ability to withstand the cold climate of the Tibetan plateau, while identifying specific genes related to hair growth, pigmentation, and heart development.

This article discusses the MendelVar webserver, which integrates Mendelian disease data with GWAS findings to prioritize candidate genes for complex traits and reports no new experimental results.

In this study, the researchers analyzed skin samples from Dun Mongolian horses to uncover molecular pathways linked to the "Bider" marking, identifying differential gene expression and several pigment-related signaling pathways that may play key roles in its formation.

This study found that the differential expression of α- and β-keratin genes in feathers may explain their morphological and structural diversity, highlighting the chicken as a model for studying keratin-related diseases.

This study identified genetic variations associated with black and white wool color in Gangba sheep, enhancing understanding of wool color genetics and aiding selective breeding for specific wool colors in Tibetan sheep.

This study developed a new analytical method to identify a wide range of endocrine disrupting compounds in full-term amniotic fluid, revealing diverse substances with potential endocrine activity.

This study on male rats found that finasteride treatment led to the differential expression of several genes in the hypothalamus and hippocampus, hinting at potential links to observed side effects like depression, anxiety, and cognitive disturbances.

This study found that gene therapy using a mouse cytomegalovirus vector with telomerase reverse transcriptase or follistatin significantly extended lifespan and improved health markers in mice, without adverse effects.

This study identified CD28, GZMB, and CD1C as key immune regulators in alopecia areata, highlighting CD28 as a potential therapeutic target with a promising safety profile, using a proteome-anchored multi-omics approach to uncover actionable targets for this autoimmune hair-loss disorder.

In this study, researchers evaluated drug-target interaction data from three major resources and developed a framework for drug repurposing, revealing associations between drug properties and therapeutic groups to aid in compound prioritization and predicting repositioning opportunities for existing drugs, particularly in cancer treatment.