Dietary And Genetic Aspects Of Polycystic Ovary Syndrome In Polish Women: Part II

    July 2025 in “ PubMed ”
    Karolina Nowosad, Małgorzata Ostrowska, Paweł Glibowski, Katarzyna Iłowiecka, Wojciech Koch
    Image of study
    TLDR Genetic factors in PCOS are complex, with potential influences from the MC4R gene.
    This study examined the association between genetic polymorphisms in the CYP19, MC4R, FTO, and INSR genes and polycystic ovary syndrome (PCOS) in 50 Polish women (25 with PCOS and 25 healthy controls). The findings showed no statistically significant differences in genotype distribution between the PCOS and control groups for most genes, suggesting these polymorphisms may not be directly linked to PCOS in this population. However, deviations in the MC4R gene suggest potential genetic influences. The study emphasizes the complexity of genetic factors in PCOS and the need for further research with larger sample sizes to better understand these associations.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 18 results

      community How does hair loss and recovery work?

      in Chat  12 upvotes 11 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 3 months ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

      community C’est terrible - at my wits end

      in Female  450 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  55 upvotes 1 year ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

    Similar Research

    5 / 1000+ results