9 citations,
November 2012 in “Archives of Dermatological Research” MC4R gene variants not linked to female hair loss.
Genetic factors in PCOS are complex, with potential influences from the MC4R gene.
12 citations,
August 2019 in “BMC Medical Genetics” Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.
PCOS has a strong genetic basis, but more research is needed to fully understand it.
129 citations,
January 2019 in “Clinical medicine insights” Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.