Molecular Genetic Characteristics of the Hoxc13 Gene and Association Analysis of Wool Traits

January 2024 in “ International journal of molecular sciences ”

Hongxian Sun, Zhaohua He, Fangfang Zhao, Jiang Hu, Jiqing Wang, Xiu Liu, Zhidong Zhao, Mingna Li, Yuzhu Luo, Shaobin Li

TLDR Hoxc13 gene affects wool length in Gansu alpine fine-wool sheep.

The study examined the Hoxc13 gene's role in wool traits of Gansu alpine fine-wool sheep, finding it highly expressed during hair follicle development phases. Two SNPs in exon 1 were identified, correlating with wool length and affecting mRNA expression. The study, involving 315 sheep, suggests Hoxc13 as a potential genetic marker for improving wool quality.

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