Molecular Genetic Characteristics of the Hoxc13 Gene and Association Analysis of Wool Traits

    Hongxian Sun, Zhaohua He, Fangfang Zhao … Shaobin Li
    Studysummary This study found that higher expression of the Hoxc13 gene in specific areas of hair follicles is associated with longer wool length in Gansu alpine fine-wool sheep.
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    Research cited in this study 13

    1. Comparative Spatial Transcriptomic and Single-Cell Analyses of Human Nail Units and Hair Follicles Show Transcriptional Similarities between the Onychodermis and Follicular Dermal Papilla ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2022
    2. Bioinformatics Analysis of Evolutionary Characteristics and Biochemical Structure of FGF5 Gene in Sheep Gene · 2019
    3. The Inconsistent Regulation of HOXC13 on Different Keratins and the Regulation Mechanism on HOXC13 in Cashmere Goat (Capra Hircus) BMC Genomics · 2018
    4. Functional Hair Follicle Regeneration by the Rearrangement of Stem Cells Methods in molecular biology · 2017
    5. Determination of Secondary Follicle Characteristics, Density, Activity, and Hoxc13 Expression Pattern of Hexi Cashmere Goat Breed ˜The œanatomical record · 2015
    6. Effect of Mycophenolic Acid on Proliferation of Dermal Papilla Cells and Induction of Anagen Hair Follicles Clinical and experimental dermatology · 2015
    7. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014
    8. Many Paths to Alopecia via Compromised Regeneration of Hair Follicle Stem Cells Journal of Investigative Dermatology · 2013
    9. A Homozygous Frameshift Mutation in the HOXC13 Gene Underlies Pure Hair and Nail Ectodermal Dysplasia in a Syrian Family Human Mutation · 2013
    10. Loss-Of-Function Mutations In HOXC13 Cause Pure Hair And Nail Ectodermal Dysplasia The American Journal of Human Genetics · 2012
    11. Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
    12. Overexpression of Hoxc13 in Differentiating Keratinocytes Results in Downregulation of a Novel Hair Keratin Gene Cluster and Alopecia Development · 2001
    13. Hoxc13 Mutant Mice Lack External Hair Genes & Development · 1998