Search

everythinglearnresearchcommunity

for

Search:↓

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Capecitabine is as effective as intravenous treatments with fewer side effects, but requires careful management of Hand-foot syndrome and patient education.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.

Hydrogen peroxide and monoethanolamine in hair dye can cause dermatitis and hair loss.

Improved dermabrasion techniques in 1987 led to better treatment results for skin issues like acne scars.

The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.

Ecklonia cava polyphenols help increase human hair growth and reduce hair loss.

Mutations in certain receptors can cause diseases and offer new treatment options.

Morroniside may help hair grow and stay in its growth phase by affecting certain cell signals.

Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.

Ethosomes improve drug delivery through the skin but may have side effects like irritation.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.

Minoxidil dissolves better in ethanol-water mixtures at different temperatures, with water playing a key role.

Juniperus plants contain compounds with potential for developing various medical treatments.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

Elevated CO2 can lessen the negative impact of water shortage on soybean roots and affects specific genes.

Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

Researchers developed a method to measure plant compounds in rat blood and found they are quickly absorbed and eliminated within 36 hours.