Periungual Lesions Secondary to Chemotherapy with Docetaxel

January 2019 in “ Przegląd Dermatologiczny ”

Dawid Sigorski, Agnieszka Markiewicz, Agnieszka Owczarczyk‐Saczonek, Paweł Różanowski, Anna Kułakowska, Waldemar Placek, Aneta Lebiedzińska

docetaxel alopecia periungual lesions chemotherapy skin toxicity

TLDR Chemotherapy with docetaxel can cause painful nail and skin side effects that may lead to stopping treatment.

The document discusses the side effects of docetaxel, a common chemotherapeutic agent used in treating systemic neoplasms, focusing on its skin toxicity that can cause alopecia and periungual lesions. These lesions can lead to pain, discomfort, and cosmetic issues, potentially resulting in the cessation of therapy due to their negative impact on patients' quality of life and daily activities. The article aims to present the clinical problems faced by patients with periungual lesions during chemotherapy with docetaxel and to outline treatment and prophylactic methods from a dermatologist's perspective to prevent severe lesions.

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