TLDR Preventive measures and effective management are crucial for reducing skin side effects in cancer treatment.
The document "Prophylaxis and Management of Skin Toxicities" from April 2019 in Breast Care (Basel) discussed strategies for preventing and managing skin toxicities in cancer patients, emphasizing early identification and intervention to improve quality of life and treatment adherence. It reviewed prophylactic measures like topical steroids, moisturizers, and protective clothing, and management techniques such as dose adjustments and symptomatic treatments. The paper highlighted common dermatologic side effects, including xerosis, pruritus, exanthema, hand-foot syndrome, nail toxicities, alopecia, and mucositis, and stressed the importance of diligent skin care and appropriate use of medications. Vismodegib was noted for its high incidence of skin toxicities (57%), often leading to complete hair loss, though scalp cooling was effective in preventing alopecia. The document underscored the need for dermatologic advice in severe cases to avoid unnecessary treatment discontinuation.
44 citations,
September 2015 in “Annals of Oncology” Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.
110 citations,
August 2014 in “International journal of cancer” Scalp cooling significantly reduces chemotherapy-induced hair loss.
44 citations,
November 2010 in “Current Opinion in Supportive and Palliative Care” Many patients find hair loss from chemotherapy very distressing, and while treatments like minoxidil and scalp cooling may help, there is no sure way to prevent it.
76 citations,
August 2007 in “Supportive care in cancer” Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.
7 citations,
October 2019 in “Annals of palliative medicine” New targeted cancer drugs can cause skin side effects, and managing them requires patient education and timely care.
88 citations,
July 2014 in “Journal of the American Academy of Dermatology” Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.
1 citations,
January 2010 in “Elsevier eBooks” Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.
19 citations,
October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.
26 citations,
February 2015 in “Pediatric blood & cancer” Targeted anticancer therapies in children often cause skin side effects like rash and dry skin.
