83 citations
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June 2017 in “Journal of the American Academy of Dermatology” This study observed that most pediatric patients with alopecia areata experienced some hair regrowth after treatment with topical JAK inhibitors, and the formulations were generally well-tolerated with mild lab abnormalities in some cases.
8 citations
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July 2020 in “Dermatologic Therapy” Tofacitinib may effectively treat folliculitis decalvans.
April 2022 in “Jurnal Penelitian Farmasi dan Herbal” In this study, hair tonic containing 15% patchouli leaf extract showed the greatest hair growth in rabbits, with higher concentrations leading to faster regrowth.
April 2025 in “Mutiara Jurnal Penelitian dan Karya Ilmiah” In this study of Beauty and Aesthetics students, researchers found that using a hair tonic made from Green Spinach Leaves significantly reduced hair loss when applied weekly, compared to a control, but no significant difference was observed when increasing application to twice weekly.
April 2024 in “Cosmetics” In this review, the authors explore how wigs can significantly improve the quality of life for individuals with alopecia areata by providing emotional benefits and serving as a coping mechanism for hair loss, while also addressing economic considerations and potential barriers to their use.
3 citations
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August 2019 in “Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran dan Ilmu Kesehatan” In this study on New Zealand white rabbits, the researchers reported that a hair tonic formula combining bitter melon leaf and carrot extracts resulted in optimal hair growth, particularly at a 3:1 ratio and a concentration of 3%, without causing irritation.
1 citations
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November 2017 in “JFL : Jurnal Farmasi Lampung” In this study, researchers found that hair tonic formulations containing Nothopanax scutellarium extract enhanced hair growth in male rabbits over 21 days, with the 25% concentration showing comparable effects to a minoxidil-based positive control.
April 2017 in “Journal of Investigative Dermatology” This study found that a single dose of TRP significantly reduced the number of UV-B-induced actinic keratosis lesions in a mouse model and was associated with improved skin histology and minimal side effects.
2 citations
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January 2020 in “Einstein (São Paulo)” This review discusses the potential of Janus kinase inhibitors as a promising new treatment for alopecia areata, suggesting they could become a first-line therapy in the future, but reports no new clinical results.
April 2025 in “Jurnal Multidisiplin Dehasen (MUDE)” In this study, a hair tonic containing fragrant pandan leaf extract and virgin coconut oil was formulated and evaluated, with most variations demonstrating physical stability except for one formulation, which showed instability in the specific gravity test.
2 citations
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January 2024 in “Skin Appendage Disorders” In this source, it is suggested that tick saliva, containing anticoagulants like heparins, induces an inflammatory reaction on the scalp that may lead to alopecia.
July 2022 in “Forte Journal” In this study, researchers tested hair tonic formulations with varying concentrations of bitter melon extract and found that higher concentrations enhanced hair growth in rabbits, with the 15% extract showing the greatest effect without causing skin irritation.
3 citations
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February 2024 in “Journal of the American Academy of Dermatology” This source discusses that while oral JAK inhibitors are used for treating lichen planopilaris and frontal fibrosing alopecia, they carry significant risk of adverse events; two cases showed promising results using tofacitinib cream as a safer topical alternative.
SMP creates illusion of full hair, addressing various issues and bringing happiness to those with thinning hair.
24 citations
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October 2018 in “JAAD Case Reports” This paper reviews the challenges of treating alopecia areata affecting eyelashes and discusses the risks associated with traditional therapies; it reports no new clinical results.
January 2022 in “Buletin penelitian tanaman rempah dan obat/Bulletin komunikasi penelitian tanaman rempah dan obat” This study observed that a hair tonic containing 3% ethanolic extract of bidara leaves stimulated rabbit hair growth more effectively over 28 days than both distilled water and 2% minoxidil, attributing this effect to the extract's anti-inflammatory and antioxidant properties.
January 2026 in “Dermatologic Therapy” This study found that a novel topical dutasteride lotion, FOL100, demonstrated excellent safety, tolerability, and usability with promising signs of clinical benefit for mild-to-moderate male pattern baldness.
1 citations
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May 2017 in “Journal of the American Academy of Dermatology” Tofacitinib helped a teenager with severe hair loss grow hair back, but more research is needed.
September 2023 in “International Journal of Applied Pharmaceutics” This study found that a topical gel containing Minoxidil and Tofacitinib citrate showed promise for treating alopecia areata, with formulation F5 demonstrating effective drug release and stability in evaluations.
2 citations
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April 2016 in “Pharmaciana” This study found that a combination of 5% green tea leaf extract and 2.5% gotukola extract stimulated hair growth effectively, achieving a growth rate of 2.689 cm in 28 days.
2 citations
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January 2002 in “Dermatology + psychosomatics” This case study reports that a 15-year-old girl with epilepsy experienced reversible hair loss linked to topiramate adjunctive therapy.
January 2015 in “Journal of evolution of medical and dental sciences” In this study, topical tacrolimus 0.03% cream showed good to excellent response in treating alopecia areata in 70% of participants, with no cutaneous or systemic side effects observed.
49 citations
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May 2018 in “Journal of the American Academy of Dermatology” This letter discusses the limited treatment options for pediatric alopecia areata and the lack of controlled studies for therapies like systemic and off-label immunosuppressive drugs, without reporting new clinical results.
March 2017 in “Current dermatology reports” Topical JAK inhibitors can effectively treat alopecia areata and vitiligo by modulating immune responses.
July 2024 in “Journal of Investigative Dermatology” Topical thyroid hormones may boost hair growth.
189 citations
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July 2009 in “The Journal of clinical investigation/The journal of clinical investigation” This review discusses how research on keratin biology has enhanced the understanding of epidermolysis bullosa simplex and indicates potential new therapeutic approaches, but it presents no new experimental results.
48 citations
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January 2024 in “Frontiers in Pharmacology” This paper reviews strategies to enhance the effectiveness of topical drug delivery by addressing skin barrier challenges, optimizing drug delivery systems, and personalizing treatment approaches, highlighting both current advancements and limitations in the field.
47 citations
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August 2024 in “Science Advances” This study introduces a new biomimetic double wound mask designed to promote scarless healing by coordinating multiple biological pathways and providing enhanced protection and nourishment to wounds.
5 citations
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April 2019 in “Ege Tıp Dergisi” This study found that applying Hypericum perforatum methanol extract-containing gel to experimental burns in rats reduced collagen discoloration and vascular damage while preserving hair follicles and epidermal thickness compared to treatment with silver sulfadiazine cream.