A Clinical Study of Alopecia Areata and the Efficacy of 0.03% Topical Tacrolimus in Its Treatment

    Srinivas Masalekar, Ramesh Bhat M, Nanda Kishore B, Sukumar Sukumar, Neeta Shetty, Jacintha Martis, Ganesh Kamath
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    TLDR Topical tacrolimus is effective and safe for treating alopecia areata.
    The study evaluated the efficacy of 0.03% topical tacrolimus in treating alopecia areata in 50 patients (33 males and 17 females) over a 12-week period. Results showed that 40% of patients with scalp involvement, 10% with facial involvement, and 4% each with eyebrow and moustache involvement had a good response, while 16% with scalp and 10% with facial involvement had an excellent response. No cutaneous or systemic side effects were observed. The study concluded that topical tacrolimus is effective for treating alopecia areata, with potential for better results at higher strengths (0.1%), and is particularly suitable for children due to its non-irritant nature and absence of side effects.
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      in Chat 4 months ago
      A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

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      in Research/Science  11 upvotes 1 year ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

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