3 citations
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February 2016 in “Pediatric dermatology” This report describes two cases of Rapp–Hodgkin ectodermal dysplasia where refractory scalp erosions improved significantly with potent topical steroids; it also suggests a potential link between these scalp conditions and erosive pustular dermatosis of the scalp in elderly patients.
15 citations
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July 2010 in “Journal of Allergy and Clinical Immunology” This study found that in mouse models, the novel NF-κB inhibitor DHMEQ improved symptoms of atopic dermatitis as effectively as tacrolimus or betamethasone.
9 citations
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January 2021 in “Mediators of Inflammation” In this study, 15d-PGJ2 administered in a topical cream inhibited oxidative and inflammatory skin changes caused by UVB radiation in hairless mice, suggesting it as a promising treatment approach.
July 2016 in “Cancer Research” This study developed a topical botanical lotion for managing chemotherapy-induced hair loss in cancer patients, reporting that it improved hair recovery times by 5-16 weeks, reduced inflammation, and enhanced scalp collagen levels with no observed side effects.
April 2024 in “International Journal Of Medical Science And Clinical Invention” This study found that transdermal application of vitamin D cream led to substantial reductions in inflammatory acne among participants with vitamin D deficiency, with all experiencing at least a 30% improvement after one month, and some achieving up to 100% reduction in acne lesions.
April 2017 in “Journal of Investigative Dermatology” In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.
January 2026 in “Biomacromolecules” This study reports that a novel nanolipogel with moderate rigidity (NLG-2.5) enhances transdermal delivery of fucosterol, displaying superior permeability, targeting hair follicles, and promoting hair growth in androgenetic alopecia model mice by inhibiting inflammation and androgen pathways and promoting angiogenesis.
3 citations
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October 2021 in “PLoS ONE” In this study, topical piperonylic acid was found to improve wound healing in mice by activating EGFR and modulating gene expression related to the healing process.
May 2003 in “Hair transplant forum international” This review discusses the use of strontium in hair restoration, noting its effectiveness for managing post-operative itching but does not present new clinical results.
7 citations
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July 2022 in “Pharmaceuticals” This study reports that pumpkin seed oil-loaded niosomes significantly decreased hair loss and increased hair growth indicators in vivo, suggesting potential as a natural anti-hair loss therapy.
19 citations
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November 2023 in “npj Regenerative Medicine” This study found that synthetic melanin particles applied topically in mouse injury models improved wound healing, showing potential as a therapy for accelerated healing, including in human skin explants.
17 citations
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January 2006 in “Veterinary Dermatology” This study found that topical melatonin and vigorous brushing did not affect hair regrowth in clipped Siberian Huskies, although lumbosacral hairs grew significantly shorter than lateral thigh hairs.
14 citations
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July 1977 in “PubMed” This study reported that a 19-year-old man's essential fatty acid deficiency was reversed with daily topical application of linoleic acid, improving clinical symptoms and normalizing certain fatty acid levels.
13 citations
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May 2021 in “Plants” This study found that the n-hexane fraction from Leea indica leaves significantly increased hair growth in mice and showed potential as a natural treatment for alopecia.
9 citations
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July 2017 in “Dermatologic Therapy” Two elderly men developed scalp inflammation after using a gel for skin lesions, which healed with treatment except for some permanent hair loss.
8 citations
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June 2024 in “Pharmaceutics” This study found that using elastic nano-liposomes to deliver palmitoylethanolamide improved its transdermal delivery and enhanced its skincare effects, with minimal cytotoxicity and no allergic reactions observed.
3 citations
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November 2021 in “Journal of The American Academy of Dermatology” This article discusses hormonal mechanisms underlying androgenetic alopecia but does not report any new findings; it reviews the roles of dihydrotestosterone and available FDA-approved treatments.
2 citations
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October 2021 in “Clinical and experimental dermatology” In this study, Cyperus rotundus essential oil was found to have significantly better depigmenting effects than hydroquinone for treating axillary hyperpigmentation, with additional benefits in reducing inflammation and hair growth, making it a cost-effective and safe treatment option.
1 citations
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June 2023 in “Cureus” In a retrospective study, researchers found that topical spironolactone improved tear film quality and reduced inflammation related to meibomian gland dysfunction and evaporative dry eye in patients, demonstrating good tolerability and suggesting it as a potential therapy for managing the condition.
March 2026 in “Preprints.org” This study investigated the secretome of adipose mesenchymal stem cells and fibroblasts used in skin care products, finding 16 therapeutic pathways involving numerous signaling mechanisms, which may offer skin benefits through anti-inflammatory and regenerative effects.
January 2026 in “European Journal of Therapeutics” In this study, researchers reported that applying topical 7.5% dapsone led to a significant decline in lichen planopilaris activity within a month and a sustained two-year remission in a patient intolerant to other treatments, suggesting dapsone as a promising alternative for managing this condition.
January 2024 in “Journal of dermatology and skin science” In this study, researchers found that applying topical aprepitant, which blocks substance P receptors, significantly reduced facial dermatitis and hair loss in rats experiencing erlotinib-induced skin side effects, highlighting the neurogenic inflammation's role and the protective effect of ROS inhibition.
January 2024 in “Pediatric Dermatology” This case study found that a 9-year-old girl with trichorhinophalangeal syndrome type 1 experienced significant improvements in hair density and length after 4 months of topical minoxidil treatment, suggesting its therapeutic potential for this condition.
April 2023 in “Journal of Investigative Dermatology” In this study, researchers found that the protein eIF4E is crucial for keratinocyte proliferation in psoriasis, suggesting it as a potential treatment target for the condition.
January 2023 in “Our Dermatology Online” An old recipe called "Champigny Saumure" might help treat a rare scalp condition.
April 2016 in “Journal of The American Academy of Dermatology” A botanical lotion can increase scalp collagen and extend hair growth phase, potentially improving hair thinning issues.
May 2015 in “Cancer Research” This study found that a new treatment candidate may effectively prevent and promote recovery from chemotherapy-induced alopecia by normalizing apoptosis and reducing inflammation in cancer patients.
July 2012 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study shows that many acne patients use topical steroids despite their association with various skin side effects, such as worsened acne, perioral dermatitis, and telangiectasias.
July 2026 in “International Journal of Innovative Technologies in Social Science” This review found that while treating keratosis pilaris is challenging, current therapies can lead to significant improvement, particularly when tailored to the individual's specific disease phenotype and concerns.
July 2026 in “Clinics in Dermatology” This review discusses the potential benefits of topical melatonin in aesthetic dermatology, including its antioxidant and protective properties for skin aging and photoaging, while also noting varying strengths of evidence across different skin conditions.