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Minoxidil boosts hair growth by activating PGHS-1.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Pumpkin seed oil may improve prostate health, bladder control, and hair growth in men.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

The combination of azelaic acid, minoxidil, and caffeine significantly increased the survival of skin flaps by affecting certain body channels and nitric oxide levels.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Targeting the skin's endocannabinoid system could help treat skin disorders.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

*Acorus calamus* has many medicinal benefits but needs more safety research.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

New treatments for hair loss may target specific pathways and generate new hair follicles.

The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.

Certain spices may help prevent and treat skin cancer, but more human trials are needed.

Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.

Saw palmetto supplements may reduce prostate cancer cell growth without being toxic.

Compounds from certain trees used by First Nations people show potential for treating skin conditions and promoting hair growth, but more research is needed to confirm their safety and effectiveness.

Black seed oil significantly protects against hair loss from chemotherapy.

Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.

The review concludes that the Ziziphus species, especially jujube, may promote hair growth and have various health benefits, warranting more research.