1 citations
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January 2019 in “Studia Biologica” This review discusses the properties and extraction methods of keratins from natural fibers and highlights their promising applications in fields such as biomedicine, bioengineering, and forensic science, but reports no new experimental results.
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November 2018 in “Elsevier eBooks” This chapter reviews the historical development of transplantology, highlighting key events and advancements in the field, without presenting new experimental results.
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January 2016 in “Frontiers in Bioengineering and Biotechnology” This study reports that keratin-based materials derived from human hair have potential for use in tissue engineering, showing promising bioactivity and mechanical support in preliminary evaluations.
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November 2014 in “Elsevier eBooks” This chapter reviews traditional and tissue-engineered treatments for skin defects and discusses advances in bioengineered skin constructs, but it presents no new experimental results.
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January 2014 in “Chinese Journal of Traditional Medical Traumatology & Orthopedics” This study concluded that high-purity rat hair follicle stem cells with strong proliferation abilities can be obtained using a modified culture and purification method.
September 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study mapped the development of the human pilosebaceous unit in prenatal scalp skin using multi-modal analysis, finding that epithelial-mesenchymal interactions guide cellular fate and validated tissue-patterning through a hair-bearing skin organoid model.
August 2026 in “Frontiers in Surgery” This review article from the examined literature highlights the shift in eyebrow reconstruction techniques from traditional methods to minimally invasive and regenerative approaches, evaluating their principles, outcomes, and challenges to inform future clinical practices.
July 2026 in “Current Stem Cell Reports” This review highlights that stem cell-based therapies show promise in skin regeneration for conditions like chronic wounds and burns due to their regenerative and immunomodulatory effects, though challenges like safety and scalability limit widespread clinical use.
March 2026 in “Materials Today Bio” This study developed a minimally invasive cryo-microneedles array patch (cryo-MAP) technique for transplanting hair follicle organoids, showing successful hair growth and complex skin structure regeneration with over 86% success in 15 days, opening new possibilities in tissue engineering.
February 2026 in “Exploration” This review summarizes research on scar formation and inhibition mechanisms, discussing emerging therapies like gene therapy and stem cell treatments, but notes ongoing challenges for clinical application, including treatment personalization and outcome sustainability.
January 2026 in “Aesthetic Surgery Journal Open Forum” This bibliometric analysis reported a significant increase in publications on hair loss treatments since 2001, highlighting new focuses on non-invasive regenerative therapies like platelet-rich plasma, microneedling, and JAK inhibitors, but emphasized the need for further high-quality clinical trials to confirm their effectiveness.
December 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” This review reports that the treatment of androgenetic alopecia is shifting from single therapies to personalized, multimodal approaches incorporating both traditional and emerging pharmacologics, regenerative strategies, nutraceuticals, cosmeceuticals, and device-based interventions, with combination regimens showing improved outcomes.
October 2025 in “Journal of Translational Medicine” This literature review discusses the challenges and potential strategies for creating fully functional hair follicles capable of active cycling, emphasizing the molecular mechanisms, signaling pathways, and innovative regenerative techniques, such as hair micropatterning and three-dimensional printing, crucial for optimizing hair follicle regeneration.
October 2025 in “Cell Transplantation” This review discusses recent advancements in hair loss treatments, including stem cell and hair follicle cell therapies, growth factors, extracellular vesicles, gene therapy, and tissue engineering, highlighting their potential in improving hair regeneration and follicle health.
March 2025 in “Wound Repair and Regeneration” In a study using mouse models, researchers developed a gelatin methacryloyl scaffold with calcium-doped silica nanoparticles loaded with deferoxamine, which significantly improved skin flap survival and hair follicle growth, suggesting potential clinical applications in tissue regeneration.
January 2025 in “Burns & Trauma” This review paper highlights that titanium dioxide nanoparticles (TiO2 NPs), due to their biological properties like antioxidant, anti-inflammatory, and antimicrobial effects, show promise in accelerating wound healing and enhancing tissue regeneration when used in scaffolds and dressings.
December 2024 in “African Journal of Biomedical Research” This review discusses the potential of 3D bioprinting to revolutionize cosmetic treatments through personalized skin regeneration, facial reconstruction, and anti-aging therapies, while highlighting the current challenges and promising future in the field of cosmetology.
December 2024 in “Regenerative Biomaterials” This paper reviews strategies for modifying the structure and protein delivery of electrospun nanofibrous materials, emphasizing their potential to guide tissue repair and highlighting current challenges and future research directions in this emerging field.
May 2024 in “Journal of drug delivery science and technology” This review highlights the potential of exosomes, particularly those derived from mesenchymal stromal cells, for treating skin conditions and regeneration, but it also identifies challenges in their production and application.
April 2024 in “Journal of translational medicine” This review highlights the diverse roles of melanocytes in pigmentation, immunity, and hearing among other functions, their involvement in disorders, and their emerging potential in regenerative medicine, including applications in disease modeling and therapy development using advanced technologies.
This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.
November 2023 in “Applied sciences” This study found that platelet dry powder can be mass-produced from pig blood by adding calcium chloride, resulting in a stable material with high growth factor concentrations, which could enhance supply for industrial product development.
October 2023 in “Biomaterials” This review highlights the potential of nanotechnology for hair follicle regeneration, focusing on strategies such as hair cycle modulation, progenitor cell stimulation, and wound-induced hair neogenesis, while also discussing regulatory challenges that may affect the development of these innovative approaches.
This review summarizes the current applications and mechanisms of self-assembled peptide hydrogels in promoting skin, bone, and nerve regeneration, highlighting their potential due to their biocompatibility and supportive role in tissue healing.
This review highlights that nanotechnology offers promising avenues for enhancing drug delivery and developing new therapeutic strategies for androgenetic alopecia, though challenges remain in clinical translation and the need for long-term safety studies.
April 2023 in “Dentistry” This chapter reviews the potential of stem cells from discarded deciduous teeth in regenerative medicine and dentistry, with no new clinical results presented.
This study found that the RADA-GHK and RADA-KGHK peptide hydrogels improved wound healing and cell growth without cytotoxicity, suggesting potential for use in skin regeneration.
November 2022 in “NATIONS UNIVERSITY INTERNATIONAL JOURNAL OF MULTI-DISCIPLINARY STUDIES” Minoxidil and finasteride are common but limited treatments for hair loss, with new therapies showing promise.
October 2022 in “IntechOpen eBooks” This source highlights the challenges in treating cicatricial alopecia, noting that follicular unit extraction hair transplantation offers a minimally invasive and successful option to improve cosmetic outcomes for patients with permanent hair loss from scarring.
January 2022 in “Stem cell biology and regenerative medicine” This review discusses strategies for hair follicle regeneration using tissue engineering and reports no new clinical results; the authors highlight potential future directions for promoting hair neoformation.