Human Hair Keratin Templates for Biomedical Applications

    January 2016 in “ Frontiers in Bioengineering and Biotechnology ”
    Ng Kee Woei
    TLDR Human hair keratin is a promising and sustainable biomaterial for tissue regeneration.
    The study explored the use of human hair keratin as a biomaterial for tissue engineering and regenerative medicine. Researchers developed various keratin-based templates, including hydrogels, sponges, and fibrous mats, and evaluated their properties. The keratin hydrogels supported fibroblast proliferation and reduced contraction compared to collagen hydrogels. Keratin-alginate sponges provided structural support and enhanced bioactivity, showing comparable performance to commercial wound dressings. Electrospun keratin fibers supported fibronectin deposition by fibroblasts. In vivo trials in mice showed no significant immunological reactions, and keratin-alginate sponges supported significant tissue regeneration. The study concluded that human hair keratin is a viable and abundant biomaterial for biomedical applications.
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