44 citations
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January 2021 in “Research” This study explored the use of manganese-doped calcium silicate nanowire-incorporated alginate hydrogels (MCSA hydrogels) for treating melanoma and promoting wound healing, finding that these hydrogels effectively ablate melanoma under near-infrared irradiation and enhance vascular endothelial cell activity for tissue regeneration.
26 citations
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March 2013 in “Journal of Biomedical Materials Research Part A” This study demonstrated that PEGDA hydrogel microwells successfully supported cell survival and proliferation while mimicking hair follicle architecture in vitro, suggesting a potential tool for hair follicle engineering.
18 citations
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January 2013 in “International Society of Hair Restoration Surgery” This article discusses the importance of clinical biopreservation for cells and tissues in hair transplantation and regenerative medicine, reporting no new empirical findings.
5 citations
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March 2017 in “Cell and Tissue Banking” In this study, noncultured autologous skin cells prepared using a tissue homogenizer significantly improved burn wound healing in rats compared to a control treatment.
4 citations
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October 2017 in “Advances in tissue engineering & regenerative medicine” In this study, a bioengineered construct using a biodegradable polycaprolactone mat cocultured with human keratinocyte and rabbit dermal fibroblast cells demonstrated potential as a tissue-engineered skin substitute, showing good cell adhesion and growth.
1 citations
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March 2021 in “Korean Journal of Clinical Laboratory Science” This study reported that oral administration of Aucklandia lappa Decne. extract significantly promoted hair growth and increased the number of hair follicles in hair-removed mice compared to controls.
May 2026 in “International Journal of Drug Delivery Technology” This review discusses PRP therapy's history, mechanisms, and innovations in its use across various medical fields, but provides no new clinical results; the authors highlight challenges like standardization and regulatory issues.
March 2026 in “Materials Today Bio” This study developed a minimally invasive cryo-microneedles array patch (cryo-MAP) technique for transplanting hair follicle organoids, showing successful hair growth and complex skin structure regeneration with over 86% success in 15 days, opening new possibilities in tissue engineering.
August 2025 in “Plastic and Aesthetic Research” This review discusses recent advancements in microneedle technology for hair loss treatment, highlighting their ability to enhance drug delivery and improve hair follicle survival in transplantation, while also exploring their potential integration with tissue engineering to address regeneration challenges.
45 citations
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August 2013 in “Facial Plastic Surgery Clinics of North America” This article reviews factors affecting follicular unit extraction, emphasizing the need to tailor procedures to individual patient characteristics, but reports no new experimental findings.
4 citations
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October 2019 in “Acta Médica Costarricense” This study highlights that while platelet-rich plasma is showing promise across multiple medical fields like dentistry and sports medicine, a lack of standardized protocols and robust clinical trials limits its routine clinical application.
June 2026 in “International Journal of Molecular Sciences” This review discusses the potential benefits and challenges of using extracellular vesicles in aesthetic medicine but reports no new clinical results, highlighting the need for rigorous validation and stronger regulatory oversight.
March 2026 in “International Journal of Innovative Technologies in Social Science” This review summarizes current clinical evidence on platelet-rich plasma, highlighting its effectiveness in treating androgenetic alopecia and as an adjunctive therapy for acne scars, while noting challenges in standardizing preparation techniques.
August 2024 in “OBM Transplantation” This article reviews the use of platelet concentrates in regenerative medicine and highlights the need for standardized protocols and more specific clinical studies, without reporting new clinical results.
January 2022 in “Plastic and Aesthetic Research” This review explores techniques for scalp reconstruction, focusing on local flap design and execution, without reporting new clinical findings.
88 citations
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December 2018 in “Advanced Healthcare Materials” This review outlines the current state and future prospects of using layer-by-layer self-assembly for cell encapsulation in biomedical applications, such as cell-based biosensors, transplantation, and tissue engineering, while also discussing its limitations and potential advancements.
7 citations
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September 2003 in “Journal of Investigative Dermatology” In this study, researchers found that thrombin may influence cyclic hair growth through its receptor PAR-1, although it does not seem to stimulate dermal papilla cell proliferation physiologically.
4 citations
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September 2020 in “Stem Cell Research & Therapy” In this study, xenobiotic-free human multipotent adult progenitor cells were found to improve wound vascularization and healing in mice, suggesting potential applicability for clinical use in humans.
4 citations
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March 2008 in “Korean Journal of Chemical Engineering” Mesenchymal cells can significantly boost human hair growth and longevity.
1 citations
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September 2022 in “Biomaterials advances” This study used 3D bioprinting to implant epidermal stem cells, skin-derived precursors, and Matrigel into mouse wounds, successfully regenerating hair follicles and skin components within four weeks, with minimal impact on stem cell viability and stemness.
February 2024 in “Bioengineering” This study found that a hydrogel formulation containing insulin, chitosan, and hydroxypropyl methyl cellulose improved wound healing in diabetic mice, promoting faster wound closure and organized tissue formation, with in vitro tests showing no cytotoxicity and enhanced cell migration.
January 2020 in “한국공업화학회 연구논문 초록집” This study found that microencapsulated dermal papilla cells in hyaluronic acid/collagen hydrogel retained their ability to initiate hair follicle regeneration, suggesting potential for alopecia treatment.
11 citations
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July 2010 in “Journal of the American Academy of Orthopaedic Surgeons” This article reviews the varied clinical outcomes of using platelet-rich plasma for connective tissue healing, highlighting inconsistencies due to differences in PRP preparations and applications, and reports no new clinical findings.
46 citations
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October 2023 in “Science Advances” In this study, researchers used 3D bioprinting to successfully create engineered skin tissues with hair follicle-like structures, potentially enhancing skin grafts and safety testing for chemical compounds by more closely mimicking natural skin complexity.
5 citations
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September 2022 in “Journal of Investigative Dermatology” This review discusses factors affecting wound-induced hair neogenesis in mice and reports no new results; it aims to facilitate meaningful comparisons of experiments across different laboratories.
5 citations
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January 2013 in “Otorhinolaryngology clinics : an international journal” This review discusses the use of platelet-rich plasma in cosmetic surgery, highlighting its expanding applications and promising potential in aesthetic treatments, but reports no new empirical findings.
July 2026 in “Regenerative medicine reports .” This study concluded that nanoparticle-based delivery systems may significantly enhance wound healing and tissue regeneration in third-degree burns, though challenges like nanoparticle variability and cytotoxicity remain.
September 2016 in “Toxicology letters” The researchers reported that hydrogels made from methacrylated glycol chitosan and hyaluronic acid with chondroitin sulfate may be suitable for load bearing soft tissue repair, showing enhanced chondrocyte viability and metabolic activity.
December 2013 in “대한기계학회 춘추학술대회” This research demonstrates that a temperature controllable medical chilling device using thermal electric cooling technology effectively maintains constant cell temperatures, potentially improving tissue viability during hair transplant procedures.
6 citations
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October 2014 in “International Journal of Molecular Sciences” Tanshinone IIA helps protect tissue from low oxygen damage by activating certain cell pathways.