Morphological Analysis of In Vitro Human Hair Growth

    January 1993 in “ Archives of dermatological research ”
    Desmond J. Tobin, Nikki Mandir, R. Dover
    TLDR Human hair follicles can grow and stay healthy for up to 8 days in a lab setting.
    The study evaluated the histological and ultrastructural aspects of normal human hair follicles maintained ex vivo for 12 days in a serum-free medium. Anagen hair follicles showed continued viability and growth for up to 8 days, maintaining normal in vivo morphologies, including functional hair bulb melanocytes. After 8 days, signs of follicular cell interaction loss and impending involution were observed, with most follicles involuting by 12 days, displaying apoptotic-like keratinocytes and highly keratinized hair structures. The study provided the first detailed histological and ultrastructural analysis of human hair follicles in culture, suggesting that while some features of catagen were present, the mechanisms might differ.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 852 results

      community Vitamin C and hair growth PH levels

      in Product  31 upvotes 2 years ago
      The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.

      community Fevipiprant 2019!

       17 upvotes 8 years ago
      The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

      community Natural Remedies: Polyphenols and Hair Loss

       19 upvotes 5 years ago
      Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community 3 months of minoxidil foam. No fin or derma rolling

      in Minoxidil  700 upvotes 1 year ago
      This user has had success with Minoxidil foam, achieving significant hair growth in three months without using finasteride or derma rolling. They are considering incorporating a DHT reducing strategy such as finasteride in the future.

    Similar Research

    6 / 1000+ results