17 citations
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October 2005 in “Journal of Biological Chemistry” This study found that Hirosaki hairless rats experience transient activation of STAT5A in the mammary glands during early lactation, involving O-GlcNAc modification rather than Tyr-phosphorylation.
March 2026 in “Journal of Zhejiang University (Medical Sciences)” This study reported that in mice with rapamycin-induced thymic atrophy, Angelica sinensis promoted thymic cortical regeneration and functional recovery by activating the Wnt/CTNNB1/Foxn1 signaling pathway and improving inflammatory microenvironment, suggesting its potential benefit against immune aging.
July 2024 in “Medical alphabet” In this review, researchers discuss the factors contributing to early graying, such as genetic predisposition, oxidative stress imbalance, and nutrient deficiencies, and highlight potential restoration methods involving palmitoyl tetrapeptide-20 and the endocannabinoid system in hair follicles.
52 citations
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January 2003 in “Journal of Investigative Dermatology” This study found that thrombospondin-1 plays a critical role in hair follicle cycle regulation, with deficiency prolonging follicle growth and overexpression delaying it through antiangiogenic effects.
24 citations
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January 2003 in “Journal of Investigative Dermatology” In this study, a synthetic antagonist of the p75 neurotrophin receptor was found to significantly inhibit hair follicle regression in murine skin cultures, suggesting a potential role in treating hair disorders characterized by premature catagen entry.