13 citations
,
March 2013 in “International Journal of Cosmetic Science” This study reports that the tetrapeptide AcSDKP significantly promotes skin and hair health in vitro and ex vivo, suggesting it could be used cosmetically to counteract skin aging and hair loss.
June 2021 in “Archives of Advances in Biosciences” This study suggests that finasteride at doses of 5 mg/kg BW or higher may adversely affect spermatogenesis and male fertility in NMRI mice.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that incorporating Lef-1 transfected dermal papilla cells into human skin equivalents significantly promoted hair follicle differentiation and hair fiber growth, offering a potential advancement for managing skin loss.
12 citations
,
August 2015 in “Plastic Surgery” This study found that botulinum toxin type A significantly reduced skin flap necrosis in rats exposed to cigarette smoke, suggesting it may help improve flap viability in smokers.
3 citations
,
January 2016 in “BioMed research international” This study found that calcium microcapsules exhibited better biocompatibility and cell viability than barium microcapsules for scaffolding in artificial dermal papilla, suggesting potential for developing new hair follicle structures.
January 2019 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This study found that the treatment group experienced a higher average increase in hair counts than the placebo group, but the difference was not statistically significant.
47 citations
,
January 2016 in “MethodsX” This study found that while the reproducibility of hair cortisol measurements in captive chimpanzees was high, the fineness of homogenized hair, sample weight, and extraction time influenced absolute cortisol concentrations.
294 citations
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January 2016 in “Stem Cells International” This review discusses the characteristics, biomaterials, and tissue engineering methods for adipose-derived stem cells in a 3D environment, highlighting their potential in regenerative medicine without presenting new clinical results.
182 citations
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June 2017 in “Biomaterials” This study found that adipose-derived mesenchymal stem cells produced more anti-inflammatory and pro-angiogenic cytokines on electrospun scaffolds, which enhanced wound healing and macrophage activity in a rat model.
76 citations
,
December 2018 in “Aesthetic Plastic Surgery” This review discusses various aesthetic and regenerative applications of platelet-rich plasma and concludes that it has potential as a safe cosmetic intervention but requires further studies to understand its clinical effects.
71 citations
,
May 2007 in “The FASEB journal” This study found that human hair follicles express erythropoietin and its receptor, suggesting these follicles may use erythropoietin signaling to modulate apoptosis under stress conditions like hypoxia and chemotherapy.
15 citations
,
February 2009 in “Cell Stem Cell” This study found that hair germ cells, derived from bulge stem cells, respond faster to dermal papilla signals and have limited proliferation compared to bulge cells during hair regeneration.
11 citations
,
May 2018 in “Philosophical Transactions of the Royal Society B” This review covers recent developments in materials for in vitro and in vivo stem cell manipulation, highlighting innovative substrate properties but does not report new experimental results.
10 citations
,
January 2011 in “Journal of Cutaneous and Aesthetic Surgery” This review discusses various surgical methods for treating baldness and reports no new results, focusing instead on the evolution and current roles of these techniques.
6 citations
,
July 2025 in “Advanced Materials” This review discusses cell membrane-coated scaffolds in tissue engineering, emphasizing their potential to enhance therapeutic outcomes in regenerative medicine and reporting no new experimental results.
1 citations
,
November 2023 in “Biomaterials advances” This study found that combining mesenchymal stromal cells from adipose tissue and hair follicles with soy protein and β-chitin scaffolds significantly reduced wound healing time and improved skin regeneration in vivo.
This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.
January 1999 in “Proceedings of the British Society of Animal Science” This study explored the effects of biotin and malate supplementation on hair follicle viability and enzyme activity in cultured cells, but it reports no new results.
19 citations
,
April 2015 in “Developmental Dynamics” This study reports that dynamic interactions between stem cells and their niche, influenced by macro-environmental factors, regulate regenerative behavior in integument pattern formation.
1 citations
,
October 2023 in “Journal of personalized medicine” In this study, researchers investigated genetic variants in pharmacogenes affecting tadalafil and finasteride pharmacokinetics, finding fed volunteers had higher drug exposure than fasting individuals, but genetic variation did not significantly impact pharmacokinetics after correcting for multiple comparisons.
January 2013 in “Elsevier eBooks” This review discusses spatial and temporal patterns in animals, focusing on skin appendage organs, but provides no new research findings.
17 citations
,
December 2019 in “Stem Cells International” This review examines the recent progress in using bioactive molecules for skin regenerative medicine and reports no new clinical results; the authors suggest this method could become a promising strategy for in situ skin regeneration.
13 citations
,
March 2024 in “Cell Transplantation” This review highlights the need for improved methods in cosmetic safety assessment, emphasizing the potential of engineered skin tissue for more effective detection and toxicological evaluation of cosmetic products, compared to traditional methods.
9 citations
,
March 2023 in “Biomimetics” This review discusses current strategies and materials in tissue engineering for skin regeneration, emphasizing design approaches and suggesting directions for future research; it reports no new clinical findings.
9 citations
,
February 2021 in “Frontiers in Cell and Developmental Biology” This review discusses the role of tissue mechanics and extracellular matrix in skin aging processes and highlights potential therapeutic strategies, but reports no new clinical results.
July 2026 in “Organoid Research” In this review, researchers summarize key factors in constructing skin organoids, including cell source and assembly methods, and emphasize advances such as air-liquid interface culture for improving tissue development, aiming to guide standardized protocols and future clinical applications.
October 2025 in “International Journal of Medical Science and Clinical Research Studies” In this systematic review, the researchers provide an overview of recent techniques and innovations in the surgical reconstruction of traumatic scalp injuries, highlighting various methods and factors influencing the choice of reconstructive strategy to improve patient outcomes.
January 2025 in “Dialnet (Universidad de la Rioja)” In this multicenter study, adipose-derived stem cell-enriched fat grafting achieved higher satisfaction and better clinical outcomes compared to platelet-rich plasma and hyaluronic acid filler in aesthetic interventions.
July 2002 in “Dermatologic Surgery” This study found that understanding the surgical anatomy of the scalp significantly improves outcomes in scalp surgery by reducing complications like unsightly scars and distorted hair patterns.
47 citations
,
July 2013 in “Pharmacological Reviews” This review discusses the role of pharmacological sciences in advancing regenerative medicine technologies but reports no new experimental findings; the authors advocate for increased pharmacologist involvement to drive innovations.