Stem Cell-Based Aesthetics: Integrating Regenerative Science with Patient-Centered Ethics

    January 2025 in “ Dialnet (Universidad de la Rioja)
    Arango Machado, Verónica, Azua Martínez, Martín Eduardo, Viera Heredia, Franklin Joel, Montes Prieto, Kelly Johana, Restrepo Gómez, Jacobo, Torres Garrido, Diego Arath, Acosta Cortez, Jorge Luis, Mata Olivares, Leilani Alejandra
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    Studysummary In this multicenter study, adipose-derived stem cell-enriched fat grafting achieved higher satisfaction and better clinical outcomes compared to platelet-rich plasma and hyaluronic acid filler in aesthetic interventions.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    This multicenter study with 180 participants from Mexico, Colombia, and Ecuador evaluated the efficacy, safety, and ethical perception of three aesthetic interventions: ADSC-enriched fat grafting, PRP therapy, and hyaluronic acid filler. ADSC-enriched fat grafting showed the best results, with a satisfaction score of 8.6, 72.3% volumetric retention, and superior skin elasticity, along with the lowest complication rate of 28.3%. PRP therapy offered moderate improvement and high safety, while hyaluronic acid fillers had lower durability and higher inflammatory response. Histological analysis confirmed enhanced tissue regeneration with ADSC treatment. A strong correlation between ethical perception and patient satisfaction highlights the importance of communication in aesthetic procedures. The study concludes that autologous regenerative therapies are superior, combining efficacy, biocompatibility, and ethical confidence, marking a new paradigm in aesthetic surgery.
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