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This study found that in pregnant rats, the suppression of ACTH responses to IL-1β is linked to the action of endogenous opioids and AP, with AP potentially inducing opioid inhibition through increased pENK-A expression.

The researchers developed semi-dissolving microneedle patches using TEMPO-oxidized bacterial cellulose nanofibers, which allow effective transdermal drug delivery by forming micro-channels for large drug quantities, overcoming traditional microneedles' low drug loading.

This study found that A(3)B(5) downregulates melanin production and suppresses melanoma cell growth by promoting proteasomal degradation of TRP-2.

This study found that intralesional pentoxifylline injections were effective for localized alopecia areata, with the best results observed when combined with triamcinolone acetonide.

In this case report, a 6-year-old miniature jenny with pemphigus foliaceus was effectively treated with oclacitinib maleate, with and without low-dose prednisolone, over four years without adverse effects.

In this case report, a 57-year-old Japanese woman with alopecia areata, associated with myasthenia gravis and thymoma, showed significant improvement after undergoing thymectomy and receiving high doses of glucocorticosteroids.

Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.

This study found that α-melanocyte-stimulating hormone increased melanin production in hair follicles of moulting Siberian hamsters, whereas [8-arginine]-vasotocin inhibited melanin production without affecting tyrosinase activity.

This study found that vinblastine treatment rapidly increased platelet counts in childhood refractory immune thrombocytopenia, providing effective control of bleeding symptoms, although side effects like neuropathic pain were common and resolved with dose adjustments.

This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.

This study found that subcutaneous administration of Botulinum toxin type A significantly reduced histamine-induced itch intensity and neurogenic inflammation in human skin compared to saline.

This study reports that a 15-year-old with trichotillomania showed improvement with aripiprazole treatment, though no consensus on treatment exists in the literature.

This study suggests that progesterone has both THP/GABAA-dependent and independent anticonvulsive effects in a hippocampal-kindled mouse model.

In this study, topical phenylephrine significantly reduced hair shedding and increased the force needed to pluck hair in women undergoing cosmetic procedures, suggesting its potential utility for traction alopecia.

This study found that methylprednisolone can block IgG-induced keratinocyte detachment in an animal model of pemphigus vulgaris, potentially by increasing the synthesis and modifying adhesion molecules.

This study found that the BP-3 extract from Boesenbergia rotunda, rich in panduratin A, demonstrated strong anti-adipogenesis and lipolysis effects on preadipocyte cells at non-toxic concentrations, and when formulated into a serum reduced thigh circumference and improved skin firmness in a human trial.

This study found that cepharanthine significantly inhibits EqHV-8 infection in vitro and improves lung tissue pathology in infected mice by reducing oxidative stress through specific signaling pathways, suggesting its potential as a treatment for equid herpesvirus type 8.

In this study, microneedling combined with bleomycin treatment for plantar warts improved the response time and reduced the number of treatment sessions needed, with a relapse rate similar to other injection-based methods.

In this clinical trial, patients with lichen planopilaris treated with the oral TYK2 inhibitor deucravacitinib showed significant improvement in PGA, LPPAI, and Skindex-16 scores over 24 weeks, with transcriptomic analyses indicating decreased inflammatory and immune pathway activity post-treatment.

This study found that cepharanthine may be a promising treatment for enterovirus infections, as it offered full protection to mice against lethal EV71 challenges and reduced viral titers and pathology.

This study found that peimine treatment significantly improved wound healing and tissue regeneration in mice by enhancing wound closure, granulation tissue formation, and epidermal thickness, with effects linked to activation of the Notch1 signaling pathway.

This study found that mimosine in lamtoro leaf powder causes moderate congestion and mild necrotic lesions in the pancreas of white rats, which are less severe than those caused by standard mimosine, suggesting the leaf powder's flavonoid, tannin, and protein components may reduce mimosine toxicity.

This study found that Yiqi Huayu Chinese medicine may inhibit benign prostatic hyperplasia in rats by reducing MMP-2 levels and vessel renewal, with effects comparable to finasteride.

In this animal study, agmatine exhibited a protective effect against seizures related to hormone fluctuations, with results suggesting that its anticonvulsant properties may involve interactions with central neurosteroids in female rats experiencing progesterone withdrawal.

In this study using a mouse model, the authors reported that the synthetic antioxidant TS-13 effectively inhibited tumor growth comparably to doxorubicin and reduced chemotherapy side effects, such as weight loss, splenotoxicity, and alopecia, more effectively when combined with the cytostatic treatment.

This study found that forsythoside A, a compound from Forsythia suspensa, may counteract DHT-induced hair regrowth inhibition by selectively inhibiting TRPV3 channels.

This study demonstrated that the biomimetic peptide PTP20 may help preserve hair pigmentation and reduce greying by enhancing melanocyte function and increasing melanin production in human hair follicles.

In this study, Indonesian spices were screened in silico for their potential to inhibit MMP9 and TNFα, which are involved in chronic diabetic wounds, and procyanidin was identified as the most promising therapeutic candidate due to its low binding energy to both proteins.

This review article compiles past and updated information on Tridax procumbens' traditional uses and chemical compounds, highlighting its diverse pharmacological activities such as wound healing, but emphasizes the need for further toxicological research.

This study reported that fire needle therapy improved skin lesions, increased melanocyte numbers, and boosted melanin levels in a vitiligo mouse model by upregulating the Wnt/β-catenin signalling pathway, suggesting its potential role in treating vitiligo through promoting pigmentation.