January 2022 in “Pharmaceutical Sciences Asia” This study found that alcoholic extracts from Clitoria ternatea flowers increased the proliferation of human dermal papilla cells and stimulated initial hair growth in mice, with effects similar to minoxidil.
This study found that Avicennia marina extract and its active compound avicequinone C inhibit enzymes and receptors related to androgenic alopecia, potentially supporting hair growth in cultured dermal papilla cells.
This study found that the methanolic heartwood extract of Avicennia marina significantly inhibited the enzyme 5 alpha-reductase type 1 in a cell-based assay, suggesting potential anti-androgenic effects for treating androgenic alopecia.
This study found that neurotrophins produced by balding dermal papilla cells inhibited both their proliferation and hair follicle growth in vitro, suggesting a potential role in androgenetic alopecia.
July 2025 in “The Korean Journal of Internal Medicine” This study suggests that T-cell recruitment, thrombosis, and increased vascular permeability may contribute to various symptom clusters in post-acute sequelae of COVID-19 through shared cytokine elevation.
130 citations
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November 2017 in “Frontiers in Immunology” This review explores recent findings on regulatory T cells, focusing on their unique functions in non-lymphoid tissues and new mechanisms of action, but presents no original clinical results.
1 citations
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January 2020 In this study, researchers found that cepharanthine significantly inhibited the growth of non-small cell lung cancer cells by inducing apoptosis through ROS generation and altering multiple signaling pathways, suggesting potential as a novel lung cancer treatment.
This study found that inhibiting mTORC2 in glioblastoma cells reduced DNA repair and increased apoptosis, highlighting its potential role in cancer cell survival and DNA damage response.
82 citations
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October 2019 in “Frontiers in Immunology” This review discusses the features of regulatory T cells and the modulation of Foxp3, emphasizing post-translational modifications' impact on Treg function but reports no new clinical results.
This study found that activating Toll-like receptor 3 signaling in periodontal ligament stem cells may enhance their immunomodulatory properties, suggesting potential implications for future stem cell therapy applications.
1 citations
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January 2014 in “The Journal of Dermatology” This letter discusses a case of Hepatitis C-related vitiligo in a patient with Ivemark syndrome and presents no new clinical results.
85 citations
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May 2019 in “Journal of neuroendocrinology” This review examines the neuroendocrine mechanisms underlying seasonal changes in mammals and highlights areas needing further research, reporting no new experimental results.
56 citations
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December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
32 citations
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March 2021 in “Journal of endocrinological investigation” This review covers the connection between thyroid diseases and skin conditions like alopecia, dermatitis, and vitiligo, and highlights the need for further research on the role of thyroid hormones in skin health.
June 2023 in “Research Square (Research Square)” In this study, researchers used spatial transcriptome profiling to identify immune disturbances in the peri-infundibular region of androgenetic alopecia patients’ hair follicles, finding increased CD4+ T cells with a bias toward Th2 immune responses compared to controls.
This dissertation reported that the loss of Ovol2 impairs hair follicle regeneration and wound repair in mice, highlighting its role in regulating directional migration of epithelial cells.
43 citations
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July 2014 in “Experimental Dermatology” This review explores the relationship between hair follicles and wound healing, emphasizing the importance of translating scientific findings into practical therapies for chronic wounds, but it reports no new experimental results.
This study found that 2-hydroxy-1,4-naphthoquinone was the most effective inhibitor of steroid 5α-reductase, showing stronger inhibition than avicequinone C in HaCaT cell assays.
April 2026 in “Trends in Sciences” This study found that Acanthus ebracteatus extract may promote the proliferation of human hair follicle dermal papilla cells and reported that its microemulsion was stable for 12 weeks.
In this study, collagen type I, skin fibroblasts, and macrophages did not show remarkable changes in androgenic alopecia patients' scalp tissues after treatment with 1550 nm fractional Er:Glass laser, despite improved hair regrowth.
This study found that gels containing glycyrrhizic acid and aqueous Glycyrrhiza glabra extract significantly reduced underarm hair growth in terms of area, thickness, length, and number compared to their gel bases.
This study identified pectin in early immature durian fruits and found that pectin-oligosaccharides derived from them show stronger antioxidant and antiglycation activities, with potential applications in cosmetic products.
67 citations
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February 2022 in “International Journal of Molecular Sciences” This study developed a nanofiber wound dressing combining ciprofloxacin and tetracycline hydrochloride, which demonstrated strong antibacterial activity against E. coli and S. aureus and showed good biocompatibility with human skin fibroblast cells, indicating significant potential for wound healing applications.
1 citations
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December 2023 in “Diagnostics” This review discussed the variability in measuring serum testosterone levels and emphasized the need for standardizing testing and sharing updated treatment protocols to manage male hypogonadism effectively. It also highlighted the importance of considering secondary hypogonadism causes and suggested consulting with endocrinologists for optimal management.
March 2024 in “European Journal of Neuroscience” This study, using a reporter mouse line, characterized diverse subtypes of dopaminergic neurons in the enteric nervous system, identifying unique subtypes with potential roles in gut function and disease.
1 citations
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July 2025 in “Journal of Human Immunity” This study found that administering minoxidil and PGE2 to pregnant mice with 22q11.2 deletion syndrome models corrected multiple developmental anomalies, including thymus growth and parathyroid positioning, by targeting prenatal mesenchymal differentiation.
7 citations
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April 2025 in “Science Advances” This study suggests that a biomaterial-based approach using microneedles and ion solutions to deliver SiO3 2− ions may disrupt inflammatory cycles and improve outcomes in inflammatory dilated cardiomyopathy (iDCM).
36 citations
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December 2021 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This study observed that both ritlecitinib and brepocitinib improved scalp biomarkers in patients with alopecia areata, with associations to hair regrowth seen in this phase 2a trial.
6 citations
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September 2024 in “Journal of Clinical Medicine” This review explored the relationship between autoimmune thyroiditis and various autoimmune skin conditions, highlighting shared genetic markers and immunological mechanisms, such as disrupted immune tolerance and oxidative stress, which may contribute to the development of these disorders.
September 2016 in “British Journal of Dermatology” Doctors need more training in skin cancer screening, a new treatment is effective for a skin condition, better diagnosis methods for skin cancer are available, hair loss in women may be linked to hormones and cholesterol, certain skin care products might cause hair loss, babies' skin gets weaker after birth, and a gene mutation might be linked to eczema.