2 citations
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May 2011 in “Pigment Cell & Melanoma Research” In this study, Tanimura et al. reported that loss of collagen XVII in mice leads to hair loss and pigmentation defects, potentially due to impaired TGF-beta signaling affecting melanocyte stem cell maintenance.
2 citations
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September 2004 in “Experimental Dermatology” This study found that VR1 activation in human hair follicles inhibited hair growth by suppressing proliferation and promoting apoptosis, suggesting VR1 plays an important role in hair growth regulation.
2 citations
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January 2004 in “Enshou saisei” This study suggests that beard dermal papilla cells may produce androgen-dependent growth factors that stimulate keratinocyte proliferation, while frontal scalp cells can have an inhibitory effect mediated by TGF-β1.
2 citations
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March 2022 in “Research Square (Research Square)” In this study, the expression of certain hair follicle-related genes differed between growth phases in Angora goats, with HOXC13 showing overexpression during the anagen phase, potentially influencing the mohair's shine and texture.
1 citations
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January 2026 in “Journal of Pharmaceutical Analysis” This review highlights the potential of natural compounds like terpenoids, flavonoids, and polyphenols in promoting hair regrowth for those with alopecia areata by activating growth pathways and modulating immune responses, but calls for further research to confirm their therapeutic utility.
1 citations
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September 2025 in “PLoS ONE” This study observed that in mouse fetuses, reticular contraction by actomyosin is involved in dermal regeneration, and differences in actin and α-SMA localization may determine the switch between regeneration and scar formation, suggesting potential insights for wound regeneration therapy.
1 citations
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February 2025 in “Cell Cycle” This study found that implanting hair-follicle-associated pluripotent stem cell sheets in mice significantly accelerated wound closure and reduced scar formation compared to non-implanted controls.
1 citations
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February 2025 in “Archives of Dermatological Research” This study found that transcutaneous electrical acustimulation aided wound healing in mice by enhancing expression of proteins related to signaling pathways, stress recovery, and mitochondrial function.
1 citations
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January 2025 in “Journal of Cosmetic Dermatology” This study found that increased ACE2 expression, prompted by mechanical stretch, promotes skin regeneration and reduces dermal thinning during tissue expansion by enhancing collagen synthesis, suggesting ACE2's potential to improve clinical outcomes in reconstructive surgery settings.
1 citations
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November 2024 in “Life” In this study, Desmodesmus pannonicus water extract demonstrated significant antioxidative properties, inhibited melanin production, promoted wound healing in human keratinocyte cells, and showed potential for hair growth enhancement in human follicle dermal papilla cells, suggesting its promise for future dermatological applications.
1 citations
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July 2024 in “Journal of Investigative Dermatology” MPZL3 protein affects hair growth cycles and could help manage hair loss.
1 citations
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May 2024 in “Preprints.org” This study observed that age influences fur quality and hair follicle traits in Rex rabbits, with significant differences in the Wnt10b/β-catenin signaling pathways during hair follicle development, suggesting the ideal slaughter age should not be earlier than 120 days to maximize fur characteristics.
1 citations
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January 2024 in “International journal of molecular sciences” This review article addresses how the TRPV4 ion channel helps cells respond to mechanical and environmental stimuli, discussing its role in calcium signaling crucial for tissue repair and fibrosis across various organ systems, and highlighting potential therapeutic targets from animal and disease models.
1 citations
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August 2023 in “Biomolecules & therapeutics” In this study, researchers found that recombinant human HAPLN1 promoted hair growth in mice and human hair matrix cells by activating specific signaling pathways, suggesting it may offer a potential hair loss treatment with fewer side effects than existing medications.
1 citations
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July 2023 in “Journal of Biophotonics” This study found that red light at an irradiance of 8 mW/cm² was most effective in promoting growth and modulating signaling pathways in dermal papilla cells treated with dihydrotestosterone, suggesting the need for personalized photobiomodulation treatment approaches for androgenetic alopecia.
1 citations
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March 2023 in “Pharmaceutics” This study found that PBMCsec has anti-fibrotic effects on mouse and human skin scars by regulating pro-fibrotic gene expression and inhibiting myofibroblast differentiation and elastic fiber breakdown.
1 citations
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March 2023 in “International journal of rheumatic diseases” This study observed that first-degree relatives of SLE patients display unique clinical and immunological profiles, showing elevated ANA titers and specific autoantibody patterns compared to healthy individuals.
1 citations
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February 2023 in “All Life” This study identified proteins involved in hair follicle formation in cashmere goat embryos, highlighting potential signaling factors that may drive hair follicle initiation and cashmere growth.
1 citations
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December 2022 in “Genes” This study found that recombinant oleosin-hFGF5 expressed in Arabidopsis can inhibit hair regeneration by decreasing the proliferation of hair follicle epithelial cells.
1 citations
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September 2022 in “Evidence-based Complementary and Alternative Medicine” In this study, Gardenia florida fruit extract promoted hair growth in vitro and in vivo by enhancing hair growth-promoting gene expression and increasing hair follicle number, size, and depth in mice.
1 citations
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March 2022 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that HIF-P4H-2 function in FoxD1-lineage cells is crucial for normal hair follicle development and homeostasis in mice, implicating disrupted HIF, TGF-β, and Notch signaling pathways in associated defects.
1 citations
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October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that targeting HSP70 can suppress basal cell carcinoma growth, underscoring the importance of tumor microenvironment interactions in cancer progression.
1 citations
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September 2021 in “Skin appendage disorders” This systematic review of five studies found that intradermal and intramuscular botulinum toxin injections showed promising hair growth outcomes for men with androgenic alopecia, but emphasizes caution due to a lack of control groups and small sample sizes.
1 citations
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February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that electrospinning membranes with smaller fiber diameters significantly improved skin wound healing by promoting cell proliferation and encouraging reparative macrophage transformation.
1 citations
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February 2021 in “Cosmetics” This study found that the ethyl acetate extract of Fagraea berteroana fruits and its fraction FEAE-F0 promoted cell proliferation and modulated gene expression in hair follicle cells, suggesting potential for hair growth stimulation.
1 citations
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January 2021 in “SSRN Electronic Journal” In this pilot study, the researchers observed that transplanting anagen hair follicles into human scars can promote remodeling of fibrotic tissue and inhibit pro-fibrotic factors, offering potential new treatments for mature scars.
1 citations
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April 2020 in “Journal of The European Academy of Dermatology and Venereology” This letter to the editor comments on the association between androgenetic alopecia and increased scalp hardness, exploring the possible role of phosphodiesterase inhibitors but provides no new clinical results.
1 citations
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November 2019 in “The Korea Journal of Herbology” In this study, a herbal mixture (RAA) was found to promote hair growth in mice, showing increases in hair density and follicle size similar to minoxidil treatment.
1 citations
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July 2019 in “Clinical Rheumatology” Leflunomide is more likely to help treat alopecia areata than cause it.
1 citations
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March 2019 in “KnE life sciences” This case report suggests that human dermal papillae conditioned media may accelerate wound healing in congenital aplasia cutis due to varicella infection.