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In this study, researchers observed increased hormone levels such as testosterone and LH in both obese and non-obese women with Polycystic Ovary Syndrome, but concluded that the enzyme 3βHSD shows poor diagnostic value for PCOS compared to healthy women.

Randomized trials reported that testosterone therapy improved sexual function in postmenopausal women with hypoactive sexual desire disorder, particularly those who had undergone oophorectomy, with reversible and well-tolerated side effects.

In this case review, researchers describe a 17-year-old transgender male experiencing clitoromegaly, hirsutism, and oligomenorrhea, investigating conditions like PCOS and non-prescription testosterone use for gender affirmation, and highlighting the importance of gender-affirming care to improve mental health outcomes.

In this systematic review, researchers observed that Toxoplasma gondii infection is associated with alterations in testosterone levels, generally increasing in humans but showing mixed effects in animals, highlighting a complex relationship that warrants further investigation.

This study found that an oral testosterone formulation normalized serum testosterone levels and significantly reduced SHBG in men with experimentally induced hypogonadism after nine days of treatment, suggesting potential efficacy for testosterone deficiency.

This study describes a postmenopausal woman's diagnosis with ovarian hyperthecosis, confirmed by a GnRHa test normalizing testosterone, highlighting hormone therapy as a therapeutic option when surgery is not feasible.

This narrative review concludes that long-term randomized controlled trials are needed to establish clear guidelines for testosterone therapy in women, given the lack of FDA-approved formulations and the variable quality of current treatments.

Among postmenopausal women, this case study observed that a rare ovarian tumor called thecoma, found via MRI, was associated with high testosterone levels and symptoms of mild virilization such as hirsutism, indicating surgery as the primary treatment.

This study describes a functional disorder in the ovary, known as stromal hyperplasia, characterized by the proliferation of ovarian stroma and luteinization of stromal cells, which is linked to excessive androgen production and elevated testosterone levels.

This case report describes a 58-year-old woman whose virilization symptoms were linked to a steroid tumor of the ovary, emphasizing the importance of prompt diagnosis and treatment to improve her quality of life.

This case report describes a 23-year-old woman with an adult granulosa cell tumor of the ovary, whose symptoms and hormone levels improved significantly after surgical removal of the tumor.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

This review discusses the impact of testosterone therapy on postmenopausal women's sexual function and well-being but notes a lack of long-term safety studies and debates on defining androgen insufficiency.

This case report describes a rare instance of virilizing androgen production due to an ovarian serous cystadenoma in a 59-year-old woman, with testosterone levels normalizing after its removal.

In this case report, a 66-year-old postmenopausal woman with hyperandrogenism and alopecia underwent bilateral salpingo-oophorectomy, which revealed rare synchronous ovarian tumors causing virilization, highlighting the importance of surgical exploration despite normal imaging.

In this study, serum omentin-1 levels were significantly higher in females with idiopathic hirsutism compared to those with PCOS and healthy controls.

This study suggests that circulating androgens produced by the testes have limited clinical relevance to major depressive disorder in adult men, but certain androgens may be linked to specific MDD symptoms.

The authors propose that higher testosterone levels in hospitalized COVID-19 patients might be associated with worse outcomes.

This case report describes a postmenopausal woman with virilization and an ovarian steroid cell tumor, highlighting the rarity and diagnostic importance of such tumors in this demographic.

This study found a weak positive correlation between dihydrotestosterone levels and C-reactive protein in COVID-19 patients, particularly in those with low testosterone, suggesting potential inflammatory effects.

This review examines the evaluation and management of hirsutism and hyperandrogenism in postmenopausal women and reports no new clinical findings.

In this study, oral testosterone administered three times daily normalized serum testosterone levels in men with experimentally induced hypogonadism over nine days and significantly reduced SHBG.

In this study, finasteride treatment for male pattern baldness improved hair loss and reduced prostate size, while increasing testosterone levels and altering steroid hormone ratios without affecting gonadotropin levels.

In this study, a dog with alopecia and a Sertoli cell tumor showed hyperprogesteronemia, and its hair regrew after castration, with progesterone levels reducing toward normal.

This review discusses female androgen insufficiency syndrome and reports no new clinical results; the authors suggest that testosterone replacement may alleviate symptoms like loss of libido and fatigue.

This study presents two adolescent cases of ovarian hyperthecosis, a rare cause of severe hyperandrogenism, highlighting management strategies involving gonadotropin suppression and hormone replacement after excluding androgen-producing adrenal and ovarian tumors.

This report describes a complex case of postmenopausal hyperandrogenism with virilization and concurrent rare ovarian tumors, highlighting the critical role of interdisciplinary collaboration in diagnosing and managing such challenging scenarios.

Low testosterone levels may lead to more severe COVID-19 outcomes.

This study observed that serum levels of oestradiol, testosterone, and androstenedione increase rapidly with the onset of puberty and continue to rise after menarche, with anovulatory cycles being common in early postmenarchal girls.