🚨 The study discusses hyperandrogenism, which is relevant to hormones affecting human hair, and mentions hirsutism, a condition related to hair growth, but it does not focus on hair loss or alopecia specifically.
TLDR Parental support and gender-affirming care are crucial for the mental health of transgender adolescents.
A 17-year-old transgender male presented with clitoromegaly, oligomenorrhea, and hirsutism, showing signs of hyperandrogenism despite not receiving gender-affirming hormone treatment (GAHT) due to parental non-acceptance. Elevated testosterone and androstenedione levels were noted, and tests ruled out virilizing tumors and nonclassical congenital adrenal hyperplasia. The case highlights the importance of parental support and ethical considerations in providing GAHT to minors, advising the patient to seek GAHT from a qualified physician and wait until age 18 for further treatment. Gender-affirming care is crucial for improving mental health outcomes in gender-diverse adolescents.
4 citations,
August 2021 in “Pediatrics in review” DSDs are birth conditions causing unusual sex development, managed with personalized care and sometimes surgery, but still lack a standard treatment approach.
32 citations,
June 2019 in “Frontiers in Endocrinology” Polycystic Ovary Syndrome (PCOS) is common in women with conditions like anovulation, hirsutism, hair loss, and type 2 diabetes, and it can lead to health risks like heart disease, obesity, insulin resistance, and depression. Non-Classic Congenital Adrenal Hyperplasia (NC-CAH) is also discussed.
1265 citations,
October 2013 in “The Journal of Clinical Endocrinology and Metabolism” The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
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150 citations,
November 2007 in “The Journal of Clinical Endocrinology and Metabolism” About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.
117 citations,
May 2017 in “Human Reproduction Update” The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
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38 citations,
May 2006 in “Archives of Gynecology and Obstetrics” Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.
19 citations,
July 2013 in “The obstetrician & gynaecologist” The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.
14 citations,
February 2016 in “Journal of Obstetrics and Gynaecology Research” Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.
1 citations,
November 2020 in “Cureus” Clinical signs of hyperandrogenism are related to female pattern hair loss severity, but biochemical markers are not.
