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research Epigenetic Effects of Gender-Affirming Hormone Treatment: A Pilot Study of the ESR2 Promoter’s Methylation in AFAB People

9 citations , February 2022 in “Biomedicines”

This study suggests that testosterone therapy in AFAB individuals may modify the methylation of the ESR2 promoter, with changes influenced by factors like total testosterone levels and age.

research Patient-reported outcomes, provider-reported outcomes, and physiologic parameters after gender-affirming hormone treatment in Canada: a systematic review

January 2025 in “HORMONES”

This systematic review reported positive outcomes with gender-affirming hormone therapy in Canada and emphasized the urgent need for standardized outcome measurement tools to enhance evidence-based practices.

research SAT645 Cardiac Autonomic Modulation In Transgender Men Under Gender-affirming Hormone Therapy

1 citations , October 2023 in “Journal of the Endocrine Society”

In this study, researchers found that transgender men exhibited impaired autonomic modulation during sympathetic stimulation compared to cisgender women, potentially due to testosterone treatment affecting cardiac autonomic modulation.

research Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society* Clinical Practice Guideline

2170 citations , September 2017 in “The Journal of Clinical Endocrinology & Metabolism”

This updated guideline from the Endocrine Society highlights the importance of endocrinologists in providing safe and effective hormone regimens for gender-affirming care, especially for adolescents who have entered puberty.

research 7288 A Preclinical Mouse Model of Gender-Affirming Hormone Therapy: Metabolic and Behavioral Outcomes

October 2024 in “Journal of the Endocrine Society”

This study observed that gender-affirming hormone therapy differentially affects metabolism in mice, with the specific metabolic impacts dependent on the type of hormonal treatment used.

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Community Join

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community I don’t understand this, is he equating taking Fin with being on HRT?

303 upvotes 1 year ago

The conversation is about using finasteride and testosterone replacement therapy (TRT) for hair loss and their role in gender-affirming care. It debates whether these treatments are considered hormone replacement therapy (HRT) and their implications for both cisgender and transgender individuals.

community Dht is a real bastard of a hormone it’s annoying to get rid of it

335 upvotes 5 days ago

DHT affects hair loss and hormonal balance, with treatments like finasteride, dutasteride, and minoxidil being discussed. Users share experiences with side effects, gym performance, and the impact on libido, with some suggesting complex treatment regimens.

community Sorry yall I cheated 😵‍💫 1 year fin + hrt

682 upvotes 10 months ago

Hair regrowth and gender transition using finasteride, estrogen, and spironolactone. Significant hair regrowth and personal transformation were achieved through hormone replacement therapy.

community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

2264 upvotes 1 year ago

A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

community ftm (21) with hairloss, advice would be great

8 upvotes 2 weeks ago

The conversation discusses hair loss treatments, specifically finasteride, for a 21-year-old FTM individual concerned about hairline recession. Users suggest finasteride and possibly topical minoxidil, while noting potential side effects like menstrual cycle return and brain fog.

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Learn

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learn Clascoterone

Can I use clascoterone if I'm undergoing gender-affirming hormone therapy? No published clinical trial has tested clascoterone in people on gender-affirming hormone therapy, so its safety in that group is unknown. The FDA label reports low systemic exposure and no described effect on blood testosterone, but it also records HPA-axis suppression and raised potassium in a small minority of subjects.

learn Hair Transplant

Does insurance cover hair transplants? Insurance usually doesn't cover hair transplants unless for specific medical conditions.

Clinics

1 / 1 results

Hair Transplant
Safe Rebirth – Gender Affirming SurgeriesBarcelona, Catalunya · ES

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