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This article reviews the use of cross-sex hormonal therapy in transmen and reports that it is reasonably safe, suggesting monitoring should be frequent initially but can be less frequent over time.

This case report suggests that ovarian steroid cell tumors should be considered in postmenopausal women with hirsutism and elevated testosterone, with surgery being effective in resolving symptoms and preventing recurrence.

Masculinization in affected individuals occurs gradually after puberty due to hormone changes.

This study of monozygotic transgender male twins observed that consistent hormone therapy led to physical changes such as deepening voice and increased facial/body hair, with no reported mood-related adverse effects.

In this study, testosterone protected female embryonic heart cells from metabolic stress by being converted into metabolites that activate estrogen receptors and up-regulate certain mitochondrial channel proteins.

This study found that hair steroid analysis effectively detected increased hormone levels from both a single testosterone dose and laboratory-induced stress, revealing individual context factors like relationship status also impact hair hormone concentrations.

This study found that applying 2.5% testosterone gel increased facial terminal hairs in young males with beta-thalassemia major and was well tolerated.

In this study, among women with polycystic ovary syndrome, free testosterone was most frequently elevated, highlighting its importance in biochemical assessment and suggesting the need for age-related interpretation of DHEAS levels.

This study found that oral estradiol was generally effective in achieving target 17-β estradiol levels in transgender women, but often failed to suppress testosterone adequately, with variability in individual responses.

This case report describes a woman with hyperandrogenism and menstrual disturbances, where an ovarian steroid cell tumor was identified and removed, leading to resolution of symptoms.

Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.

This review discusses testosterone metabolism in human skin and its role in androgenetic skin disorders, suggesting that temporary increases in dihydrotestosterone may lead to these conditions.

This case report describes a postmenopausal woman with hirsutism and hair loss attributed to ovarian stromal hyperplasia; surgical removal of the ovaries normalized testosterone levels and resolved symptoms.

This study observed that 5α‐dihydrotestosterone increased pigmentation in certain skin areas of male Syrian hamsters, while estradiol decreased melanocyte numbers and counteracted the androgen-induced pigmentation effects.

In this study, females with 5 alpha-reductase-2 deficiency exhibited decreased body hair, normal sebum production, and delayed menarche, suggesting a role for DHT in hair growth and menstrual function.

This review discusses trends in testosterone therapy use for male hypogonadism and reports no new clinical results, noting a shift towards more convenient and physiological treatments.

This article discusses hyperandrogenism, including its symptoms, causes, and diagnostic approaches, and reports no new clinical results; it emphasizes the role of interdisciplinary care in treatment.

This study found that the total testosterone/dihydrotestosterone ratio correlates with a negative metabolic profile in both women with PCOS and healthy women.

This article discusses clinical features and treatment options for hyperandrogenism in women and does not report new findings, highlighting current practices in diagnosis and management.

In this study, a 300 mcg daily testosterone patch significantly increased satisfying sexual episodes and sexual desire in postmenopausal women with hypoactive sexual desire disorder not receiving estrogen, compared to placebo.

This case report describes a 72-year-old woman with a steroid cell tumor of the ovary, highlighting the critical role of imaging, biochemical evaluation, and pathology in diagnosing and managing hormonally active ovarian tumors that cause virilization in postmenopausal women.

A woman's high testosterone levels were caused by a rare ovarian tumor, not the initially diagnosed condition.

This study observed that testosterone combined with hormonal contraceptives elevated hormones like estrone and testosterone, altered coagulation factors, and increased sexual behavior frequency in female capuchin monkeys.

This study documented a case of a 57-year-old woman with postmenopausal virilism due to a Sertoli-Leydig cell tumor, which improved after surgical treatment.

This study using Mendelian randomization suggests lifelong increased free testosterone in males may have beneficial effects such as increased bone mineral density and decreased body fat, but also increased risks of prostate cancer and hypertension.

This case study highlights the challenges of diagnosing hyperandrogenism in postmenopausal women, reporting a patient with androgenic alopecia and high testosterone due to a benign Leydig cell tumor in the ovary; surgery successfully normalized testosterone levels.

This study measured plasma testosterone glucosiduronate levels and found no overlap in those with hyperandrogenism compared to normal females, despite normal testosterone and dihydrotestosterone levels in half of the affected patients.

This study found that male liver cirrhosis patients have higher estradiol levels and lower dehydroepiandrosterone sulfate, leading to hormonal imbalances favoring estradiol, but without changing sex hormone-binding globulin's binding properties.

This review discusses the controversial cardiovascular safety and efficacy of subcutaneous testosterone therapy in postmenopausal women, noting that its long-term use appears safe, but CV risk assessments remain disputed.

In this controlled registry study, 8 years of testosterone therapy in hypogonadal men led to a significant decrease in waist circumference, weight, and BMI compared to those without the therapy.