The Effects of Single Testosterone Administration and Stress Induction on Steroid Hormone Levels in Hair

    November 2024 in “ Psychoneuroendocrinology
    Hana H. Kutlikova, Christoph Eisenegger, Aniko Krumbholz, I Riečanský, Claus Lamm, Boris B. Quednow
    TLDR Testosterone increases hair testosterone levels, stress raises hair cortisol, and relationship status affects hormone levels.
    The study on 88 healthy adult men explored the impact of a single 150 mg transdermal testosterone dose and acute stress on hair hormone levels. It revealed that testosterone administration significantly increased hair testosterone levels after 7 weeks, while stress induction elevated hair cortisol levels, indicating that hair analysis can detect hormonal changes from single events. Additionally, men in committed relationships had lower hair cortisol and testosterone levels, suggesting personal factors like relationship status influence hormone concentrations. The study underscores the importance of considering brief stressors and personal context in interpreting hair hormone data and calls for further research, including female participants, to better understand these dynamics.
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