TLDR Removing the ovarian tumor improved the woman's hormonal symptoms.
A 23-year-old woman presented with symptoms of androgen excess, including irregular menstrual cycles, amenorrhea, hirsutism, and significant weight loss. Her condition did not improve with oral contraceptives. Laboratory tests revealed elevated levels of DHEA-S, total and free testosterone, and 17-OH pregnenolone, as well as Inhibin B. Imaging showed a large ovarian mass, which was surgically removed and identified as an adult granulosa cell tumor. Post-surgery, her Inhibin B and testosterone levels decreased significantly, and her menstrual irregularities and hirsutism improved. This case highlights the impact of granulosa cell tumors on androgen levels and the effectiveness of surgical intervention.
April 2021 in “Journal of evolution of medical and dental sciences” Women with PCOS have higher levels of certain androgens, which are good at predicting excess hair growth.
26 citations
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February 2011 in “Anais Brasileiros De Dermatologia” Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.
11 citations
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July 2003 in “The Nurse practitioner” New treatments for PCOS focus on managing symptoms and improving fertility.
1 citations
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June 2019 in “Innovare journal of medical sciences” Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.
October 2016 in “Journal of the Dermatology Nurses’ Association” Polycystic Ovary Syndrome (PCOS) affects 6%-15% of women of reproductive age, causing symptoms like acne and hair loss, and increasing the risk of type 2 diabetes and heart disease; it's managed through diet, exercise, and medications like Metformin and hormonal contraceptives.
254 citations
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March 2023 in “Diagnostics” The guidelines suggest reconsidering PCOS criteria for better diagnosis and care.
