Hyperandrogenism After Menopause

    January 2013 in “ Revista Clínica Española ”
    Inés Castro-Dufourny, M. Saiz-Pardo-Sanz
    Image of study
    TLDR A postmenopausal woman's increased male hormone levels were successfully treated with surgery.
    The document reported on a 65-year-old postmenopausal woman with hyperandrogenism, evidenced by hirsutism and frontal alopecia. Hormonal analysis showed elevated testosterone and free testosterone levels, suggesting an ovarian source. After ruling out ovarian cancer, treatment with dexamethasone and a GnRH analog indicated that the hypersecretion of androgens was LH-dependent. A bilateral oophorectomy was performed, revealing ovarian stromal hyperplasia, and resulted in normalized androgen levels and improvement in alopecia and hirsutism. The case emphasized that even slight increases in androgen levels in postmenopausal women are pathological and that surgical treatment is important for benign conditions like ovarian hyperthecosis or stromal hyperplasia due to the associated risks of endometrial complications and metabolic disorders.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 8 results

      community Dutasteride is amazing even for women with FAGA!

      in Female  151 upvotes 2 weeks ago
      Dutasteride significantly improved hair health and reduced shedding for a woman with PCOS and hyperandrogenism, without causing depression or anxiety, unlike finasteride. Dutasteride also helped with PMDD symptoms and had no side effects, though it changed hair texture.

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  38 upvotes 6 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

      community Proposed new pathogenesis model for androgenetic alopecia (AGA)

      in Research/Science  8 upvotes 2 years ago
      The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Spironolactine Update: 2 months (34, Female)

      in Female  21 upvotes 8 years ago
      A female user's experience using Spironolactone to treat Female Pattern Hair Loss (FPHL) and Androgenic Alopecia, as well as discussing the effectiveness of the drug at different dosages.

    Related Research

    4 / 4 results