How Should Postmenopausal Androgen Excess Be Evaluated?

    March 2011 in “ Clinical Endocrinology ”
    Micol S. Rothman, Margaret E. Wierman
    Image of study
    TLDR Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.
    The document from 2011 reviewed the evaluation and treatment of postmenopausal hyperandrogenism, noting that excessive androgens in postmenopausal women can lead to symptoms like hirsutism and hair loss. It highlighted that there is no definitive androgen level that confirms the cause of hyperandrogenism, but levels of testosterone (T) above 200 ng/dl or dehydroepiandrosterone sulfate (DHEA-S) above 800 ng/ml historically indicated the need for tumor evaluation. The study mentioned included 60 women with androgen-producing tumors, most of whom had T levels between 100 and 200 ng/dl. Diagnostic approaches include radiologic evaluations and, less commonly, venous sampling. Treatment depends on the underlying cause and is important due to the associated health risks, including cardiovascular disease and breast cancer. The document emphasized the importance of a comprehensive evaluation involving history, examination, laboratory tests, and radiologic tests to manage hyperandrogenism in postmenopausal women effectively.
    Discuss this study in the Community →

    Research cited in this study

    5 / 5 results

    Related Community Posts Join

    6 / 1000+ results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community How does hair loss and recovery work?

      in Chat  12 upvotes 2 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community One+ year 1mg Fin, Ketoconazole, and 3.75 Oral Min. I have DUPA. Switched from Topical to Oral Min.

      in Progress Pictures  142 upvotes 2 years ago
      A user's experience with hair loss treatments such as finasteride, ketoconazole, and oral minoxidil that have not yielded any results; other users suggest shaving the head or getting a wig, while others offer additional advice such as seeing a dermatologist, checking thyroid levels, switching to dutasteride and adding needling, and trying stemoxydine.

      community Methionine? Glycine?

       6 upvotes 8 years ago
      The conversation discusses the potential benefits and risks of using Methionine and Glycine for hair loss, with concerns about cancer risk if not balanced properly. The user seeks opinions on these amino acids for hair health and overall benefits.

      community Having androgen receptor density and sensitivity at wrong f*ing place

      in Satire  7 upvotes 1 month ago
      The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

    Related Research

    2 / 2 results