TLDR Castration helped a dog with a tumor and hair loss by normalizing hormone levels and regrowing hair.
A dog with a Sertoli cell tumor exhibited hyperprogesteronemia and alopecia, with hair loss starting in the lumbar areas and a dull, dry coat. Laboratory tests showed elevated serum progesterone and incomplete cortisol suppression after low-dose dexamethasone. Following castration, the dog's hair regrew, and progesterone levels decreased toward normal.
1 citations
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January 2006 in “Elsevier eBooks” The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.
22 citations
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February 2010 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.
34 citations
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March 2003 in “Veterinary Dermatology” Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.
October 2025 in “Journal of the Endocrine Society” A rare ovarian tumor was found in a young woman with a genetic fat disorder.
April 2023 in “Clinical theriogenology” The dog's skin condition improved after removing a tumor that was causing hormone imbalances.
