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This study found that long-term finasteride therapy in men with BPH worsened erectile dysfunction and reduced testosterone levels, while these effects were not observed with tamsulosin.

This study isolated new geranylated coumarins from Mammea siamensis flowers and found that several of these compounds inhibit testosterone 5α-reductase.

This study found that a new hydrogel formulation of basic fibroblast growth factor showed promise in promoting hair regrowth and reducing inflammation in testosterone-treated mice.

This study reported that the n-butanol fraction of Perilla frutescens extract, particularly rosmarinic acid, showed potential for hair regrowth and anti-androgenic activity in male mice, suggesting it as a possible treatment for androgenetic alopecia.

This study found that KH053, combining Panax ginseng and bee-pollen, significantly reduced prostate weight and DHT levels, inhibiting BPH development in a rat model.

This study suggests that in rat skin, testosterone itself may play a more significant role in androgen action than 5α-dihydrotestosterone, unlike in the prostate where 5α-DHT is more dominant.

In a clinical trial, this study found that a modified slow-release oral testosterone formulation improved pharmacokinetics, delaying serum testosterone peaks and reducing serum DHT compared to immediate-release formulations, especially when combined with finasteride.

This study found that women with acne and oligomenorrhea have higher levels of biologically active testosterone compared to those with acne and normal menstrual cycles.

This study found that the petroleum ether extract of Citrullus colocynthis fruit and an isolated steroidal compound may reduce prostatic hyperplasia in rats induced by testosterone, suggesting potential use in managing androgen-dependent conditions.

This study found that while testosterone administration reduced myocardial damage in gonadectomized rats after ischemia/reperfusion injury, Finasteride led to greater improvements, whereas 4-hydroxyandrostenedione worsened outcomes.

In this study, testosterone and finasteride were found to increase insulin and zinc levels while decreasing chromium levels in male adult rats, suggesting potential effects on the glucose cycle.

This study systematically reviewed the use of topical testosterone products such as creams, gels, and patches, finding they effectively raise serum testosterone but pose significant systemic risks like acne and gynecomastia, necessitating careful medical oversight.

This study suggests that the testosterone analogs 7α-Methyltestosterone and 7α-Ethyltestosterone may offer promising androgenic, progestogenic, and anabolic properties for development as male contraceptives.

This study found that aqueous extract of Pueraria mirifica, when administered to a rat model, significantly reduced prostate weight, prostatic index, and serum dihydrotestosterone levels, while also improving prostate histomorphology, suggesting its potential as an anti-BPH treatment.

This study found that Helianthus annuus oil promoted hair growth in a testosterone-induced alopecia mouse model, with higher hair density observed compared to untreated mice, though it was less effective than the standard minoxidil treatment.

This study found that testosterone therapy increased bone mineral density in older men with low testosterone, and combining it with finasteride may reduce prostate enlargement associated with testosterone treatment.

This study indicated that while testosterone replacement in older men with low testosterone increases muscle mass and strength and reduces fat, its effects on physical function, disability, falls, or fractures remain unclear.

This study found that testosterone replacement, with or without finasteride, did not lead to significant cognitive improvements over 36 months in healthy older men without prior cognitive impairment.

This article discusses the potential effects of exogenous testosterone, highlighting that its impact on prostate cancer progression, cardiovascular health, and behavior remains uncertain and needs further investigation.

In this study, transgender adolescents treated with testosterone for a median of 12 months experienced effective virilization, including voice deepening and increased hair growth, but also showed decreased HDL cholesterol and BMD z-scores, and increased hematocrit, with no short-term safety issues reported.

This study found that 4 weeks of finasteride treatment significantly decreased DHT levels in bald scalp to levels similar to hair-containing scalp in men with male pattern baldness.

This study found that testosterone and 5α-dihydrotestosterone induced apoptosis in dermal papilla cells from nonbalding scalp regions, suggesting a high androgen stimulus can trigger cell death related to androgenetic alopecia.

This study suggests that red ginseng rhizome extracts, particularly ginsenoside Ro, may promote hair re-growth in an androgenetic alopecia model due to their inhibitory activity on testosterone 5α-reductase.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

This study found that a testosterone patch and gel showed bioequivalent testosterone levels in hypogonadal men, but the patch mimicked a natural circadian profile, while the gel resulted in higher dihydrotestosterone levels.

This review refutes several myths about testosterone therapy in women and suggests that testosterone is beneficial for both physical and mental health, though its safety in women continues to be researched.

Testosterone was found to inhibit hair follicle epithelial cell proliferation in adult stumptailed macaques only when dermal papilla cells from bald scalps were present, and this effect was reversed by the antiandrogen RU 58841.

This review discusses the negative health impacts of testosterone deficiency and the potential adverse effects of 5α-reductase inhibitors, emphasizing the need for patient-physician discussions regarding these treatments.

This review examines the roles of androgens in women's health and provides recommendations for androgen therapy but reports no new results.

This study found that coadministration of 5α-reductase inhibitors with oral testosterone in oil significantly increases serum testosterone levels in medically castrated men compared to testosterone alone, with food intake minimally affecting these levels.