Hair Transplantation: Causes, Techniques, and Future Prospects

    January 2010 in “ Elsevier eBooks
    David M. Schwartzenfeld, Joseph Karamikian
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    TLDR Hair transplantation is a treatment for hair loss mainly caused by genetics, with various techniques and potential complications, and results visible after 8-12 months.
    The document from January 1, 2010, discusses hair transplantation, identifying androgenic alopecia (AA) as the cause of over 95% of pattern hair loss, influenced by testosterone and dihydrotestosterone (DHT). Other causes of hair loss include metabolic, infectious, inflammatory, autoimmune disorders, trauma, and medications. It acknowledges Dr. O'Tar T. Norwood's contributions, particularly the Norwood Classification for male pattern baldness. Hair transplantation requires careful planning of the hairline, donor area harvesting, and managing the patient's donor supply, with complications such as edema, folliculitis, infection, and wound dehiscence possible. Medical treatments mentioned include finasteride and minoxidil, with future prospects like cloning and nanotechnology. Follicular unit extraction (FUE) is described as having advantages like shorter recovery and no linear scar but also disadvantages like higher rates of follicle damage and a limit of 400 to 600 grafts per session. Full transplant results can take 8 to 12 months to appear.
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      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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      Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

      community Does finasteride/dutasteride reverse aging?

      in Chat  45 upvotes 1 month ago
      Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

      community What else is good. Besides the big 3.

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      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

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