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Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.

These drugs cause hair growth without affecting testosterone or adrenal hormones.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

Spironolactone can reduce hair growth and testosterone in hirsutism, but is less effective than combined treatments.

Lespedeza cuneata extract may help treat enlarged prostate.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Alfacalcidiol and metformin together lowered testosterone in women with PCOS, but did not significantly improve acne, hair growth, or pregnancy rates.

Hormone levels in hair change during pregnancy, with progesterone increasing significantly compared to non-pregnant women.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.

Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

The treatment reduced hair growth and testosterone in women with excess hair and had some effects on stress responses.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.